… inflammatory bowel disease (96). Disrupted expression of estrogen receptors in the intestinal
… anti-secretory effect in a human colonic adenocarcinoma cell line via inhibition of KCNQ1 …

… The intestinal type of gastric adenocarcinoma is more often … Estrogens bind to estrogen
receptors causing conformational … In this way, estrogen receptors are homodimerized or …

… the status of estrogen and progesterone receptors was observed … in the pathogenesis of
inflammatory bowel diseases (IBDs) (… tumor fragments with colorectal adenocarcinoma, reaching …

… Intestinal bacterial β-glucuronidase and β-glucosidase activity have also been shown to
be induced by a high pH, which may also increase colon cancer the risk (58,59). The role of …

… the prevalent estrogen receptor in normal colon mucosa and … , immune responses in
inflammatory bowel diseases (IBD) [… APC and progresses into adenocarcinoma upon acquisition …

… with different phenotypes distinguished by their specific … , leading to adenomas and
invasive adenocarcinomas [5]. … is a predominant estrogen receptor subtype in the colon [73,132…

… -treated estrogen receptor β (ERβ) knockout mice, compared to wild-type mice. However,
almost no studies have thoroughly evaluated the early inflammation … and adenocarcinoma was …

… PTCH1, and hh-associated transmembrane receptor Smoh in hyperplastic polyps, adenomas,
and adenocarcinomas of the colon [93]. Exogenous SHH can promote the growth of colon …

… In healthy colorectal tissues, both estrogen receptors ERα and ERβ are present, with ERβ …
, with a particular increase in the risk of adenocarcinoma in the distal colon [81]. A cohort study …

… Examination of estrogen receptor status showed ERα was present in Colo205 and Caco2 …
protein coupled estrogen receptor (GPER), and that stimulation of this receptor with estradiol (…