[HTML][HTML] Intestinal epithelial glucocorticoid receptor promotes chronic inflammation–associated colorectal cancer

S Tang, Z Zhang, RH Oakley, W Li, W He, X Xu, M Ji… - JCI insight, 2021 - ncbi.nlm.nih.gov
bowel disease (IBD), a class of chronic intestinal mucosa … -cadherin was observed in colorectal
adenocarcinoma (23). … Tamoxifen is a selective modulator of estrogen receptor (45, 46), …

[HTML][HTML] Obesity and the risk of gastrointestinal cancers

J Karczewski, B Begier-Krasińska, R Staszewski… - Digestive diseases and …, 2019 - Springer
Estrogen receptor-β (ERβ) has been shown to have an … on colon, with this effect also probably
occurring in other gastrointestinal … and esophagogastric junctional adenocarcinoma when …

[HTML][HTML] Colorectal carcinoma: a general overview and future perspectives in colorectal cancer

I Mármol, C Sánchez-de-Diego… - International journal of …, 2017 - mdpi.com
… are other inherent risk factors that cannot be modified. A personal history of colorectal cancer
or inflammatory bowel disease (… ’s disease have a 2.5% higher risk of developing colorectal

Circulating sex hormones are associated with gastric and colorectal cancers but not esophageal adenocarcinoma in the UK Biobank

ÚC McMenamin, P Liu, AT Kunzmann… - Official journal of the …, 2021 - journals.lww.com
… Expressions of both estrogen receptor β and androgen receptors have been shown in
esophageal squamous cell carcinoma tissues ( 25,26 ) and in vitro evidence has demonstrated …

[HTML][HTML] Estrogens, cancer and immunity

I Orzołek, J Sobieraj, J Domagała-Kulawik - Cancers, 2022 - mdpi.com
Estrogen receptors belong to the family of transcription factors and act by … as a possible value
in colorectal cancer prevention [58]. … of ERs was reported in lung adenocarcinoma [60,61]. …

[HTML][HTML] Linking obesity with colorectal cancer: epidemiology and mechanistic insights

P Ye, Y Xi, Z Huang, P Xu - Cancers, 2020 - mdpi.com
… in low-grade colorectal adenocarcinoma, which … estrogen is mediated by its receptors,
estrogen receptor (ER)-α and ER-β. The expression of ER-α is very low in normal colorectal

[HTML][HTML] Estrogen receptor beta influences the inflammatory p65 cistrome in colon cancer cells

R Indukuri, L Hases, A Archer, C Williams - Frontiers in endocrinology, 2021 - frontiersin.org
… -wide binding in human CRC cells and correlate this to the TNFα-mediated transcriptional
impact in the same cells. We used two well-characterized human colorectal adenocarcinoma

Estrogen receptor-beta genetic variations and overall survival in patients with locally advanced gastric cancer

Y Sunakawa, S Cao, MD Berger, S Matsusaka… - The …, 2017 - nature.com
… of colorectal cancer but also gastric cancer (GC). Polymorphisms in estrogen receptor β gene,
ESR2, correlate with colorectal … type and estrogen receptors in gastric adenocarcinoma. …

[HTML][HTML] Secondary metastatic lesions to colon and rectum

M Galanopoulos, F Gkeros, C Liatsos… - Annals of …, 2018 - ncbi.nlm.nih.gov
Colorectal adenocarcinoma is typically CDX-2 positive, … CA-125, estrogen and progesterone
receptors is considered … as diverticulitis and inflammatory bowel diseases, or may mimic …

[HTML][HTML] Expression of voltage-gated sodium channel Nav1. 5 in non-metastatic colon cancer and its associations with estrogen receptor (ER)-β expression and …

J Peng, Q Ou, X Wu, R Zhang, Q Zhao, W Jiang… - Chinese Journal of …, 2017 - Springer
… All included patients met the following inclusion criteria: (1) histologically confirmed colon
adenocarcinoma; (2) pathologic stage I–III diseases according to the 7th edition of Union for …