Adiposity and gastrointestinal cancers: epidemiology, mechanisms and future directions

N Murphy, M Jenab, MJ Gunter - Nature Reviews Gastroenterology & …, 2018 - nature.com
… oesophageal adenocarcinoma and colorectal, small intestine, … Oestrogen receptor-β (ERβ)
has been demonstrated to have … ERβ inhibits proliferation in colon cancer 96 and pancreatic …

Deciphering the Molecular Mechanisms of Estrogen Signaling in Gastrointestinal Tumors

F Mesmar - 2017 - uh-ir.tdl.org
estrogen nuclear receptor in the colon is estrogen receptorbowel diseases (such as
ulcerative colitis and Chron’s … expression data for colorectal adenocarcinoma TCGACOADREAD …

Role of G protein-coupled estrogen receptor in cancer progression

J Jung - Toxicological research, 2019 - Springer
receptors are thought to be major factors. Many studies have reported the effects of estrogen
and estrogen receptors (… (GPER) expression in endometrial adenocarcinoma and effect of …

Estrogen receptor β is associated with expression of cancer associated genes and survival in ovarian cancer

S Schüler-Toprak, F Weber, M Skrzypczak, O Ortmann… - BMc cancer, 2018 - Springer
Background In ovarian cancer, the role of estrogen receptors (ERs), particularly of ERβ,
being suggested as tumor suppressor in breast and prostate cancer, remains unclear. We …

MicroRNAs in the etiology of colorectal cancer: pathways and clinical implications

AM Strubberg, BB Madison - Disease models & …, 2017 - journals.biologists.com
colorectal cancer and as prognostic indicators of this disease. MiRNAs also represent attractive
candidates for targeted therapies because their function can be manipulated through the …

Cannabinoids and endocannabinoid system changes in intestinal inflammation and colorectal cancer

V Cherkasova, O Kovalchuk, I Kovalchuk - Cancers, 2021 - mdpi.com
… expression in human specimens (24 samples of primary sporadic adenocarcinoma and …
17β-estradiol stimulates CB1 expression via the activation of the estrogen receptors ERα and ER…

Gender differences in obesity-related cancers

G Argyrakopoulou, M Dalamaga, N Spyrou… - Current obesity …, 2021 - Springer
… risk of developing esophageal adenocarcinoma, colon and rectal cancer in men, … estrogen
effects on colon cancer could be attributed to the different functions of the estrogen receptors

Estrogen receptors α and β and aromatase as independent predictors for prostate cancer outcome

T Grindstad, K Skjefstad, S Andersen, N Ness… - Scientific reports, 2016 - nature.com
… The positive tissue controls comprised ovary for ERα, colon adenocarcinoma for ERβ and
placenta for aromatase; Negative tissue controls were samples of normal pancreas and liver. …

Emerging roles of Wnt ligands in human colorectal cancer

X Nie, H Liu, L Liu, YD Wang, WD Chen - Frontiers in oncology, 2020 - frontiersin.org
… of colonic polyps or inflammatory bowel disease, and some CRC-… nuclear factor, estrogen
receptor, could significantly … high expression levels in some colorectal adenocarcinomas (64). …

Cysteinyl leukotriene 1 receptor influences intestinal polyp incidence in a gender-specific manner in the ApcMin/+ mouse model

S Savari, NK Chandrashekar, J Osman… - …, 2016 - academic.oup.com
… in patients with colorectal adenocarcinomas. Apc mutation is an … inflammatory bowel disease
patients to develop colorectal … We also compared the mRNA levels of estrogen receptors α …