[HTML][HTML] Intestinal epithelial glucocorticoid receptor promotes chronic inflammation–associated colorectal cancer

S Tang, Z Zhang, RH Oakley, W Li, W He, X Xu, M Ji… - JCI insight, 2021 - ncbi.nlm.nih.gov
bowel disease (IBD), a class of chronic intestinal mucosa … -cadherin was observed in colorectal
adenocarcinoma (23). … Tamoxifen is a selective modulator of estrogen receptor (45, 46), …

Circulating sex hormones are associated with gastric and colorectal cancers but not esophageal adenocarcinoma in the UK Biobank

ÚC McMenamin, P Liu, AT Kunzmann… - Official journal of the …, 2021 - journals.lww.com
… Expressions of both estrogen receptor β and androgen receptors have been shown in
esophageal squamous cell carcinoma tissues ( 25,26 ) and in vitro evidence has demonstrated …

[HTML][HTML] Obesity and the risk of gastrointestinal cancers

J Karczewski, B Begier-Krasińska, R Staszewski… - Digestive diseases and …, 2019 - Springer
Estrogen receptor-β (ERβ) has been shown to have an … on colon, with this effect also probably
occurring in other gastrointestinal … and esophagogastric junctional adenocarcinoma when …

[HTML][HTML] Sex differences in the incidence of obesity-related gastrointestinal cancer

JW Heo, SE Kim, MK Sung - International journal of molecular sciences, 2021 - mdpi.com
… of esophageal, liver, and colorectal cancers. We suggest that these … In the brain, estrogen
receptor (ER)-α-bound 17β-estradioldiseases, including esophageal adenocarcinoma, which …

Estrogen signaling deregulation related with local immune response modulation in irritable bowel syndrome

D Jacenik, AI Cygankiewicz, J Fichna… - Molecular and cellular …, 2018 - Elsevier
… The aim of this study was to investigate estrogen receptors … inflammatory bowel disease,
with 17α-ethynyl-17β-estradiol … between estrogen receptors expression in colon samples. P-…

Host Nuclear Receptor Activation in the Colon: Consequences for Inflammatory Bowel Diseases and Colorectal Carcinogenesis

CD Allred, RS Chapkin, A Jayaraman, BR Weeks - 2020 - oaktrust.library.tamu.edu
… activation, including that of the estrogen receptors (ER) and the aryl hydrocarbon receptor
(AhR), … Elwood Jensen and his students to discover the first estrogen receptor (ER), ultimately …

Estrogen receptors participate in carcinogenesis signaling pathways by directly regulating NOD-like receptors

W Fan, X Gao, C Ding, Y Lv, T Shen, G Ma… - Biochemical and …, 2019 - Elsevier
… In this study, we identified the regulatory role of ERs on NLRs and their effects on colon
cancer cells, which will significantly improve our understanding of NLRs in the regulation of …

[HTML][HTML] Secondary metastatic lesions to colon and rectum

M Galanopoulos, F Gkeros, C Liatsos… - Annals of …, 2018 - ncbi.nlm.nih.gov
Colorectal adenocarcinoma is typically CDX-2 positive, … CA-125, estrogen and progesterone
receptors is considered … as diverticulitis and inflammatory bowel diseases, or may mimic …

[HTML][HTML] Linking obesity with colorectal cancer: epidemiology and mechanistic insights

P Ye, Y Xi, Z Huang, P Xu - Cancers, 2020 - mdpi.com
… in low-grade colorectal adenocarcinoma, which … estrogen is mediated by its receptors,
estrogen receptor (ER)-α and ER-β. The expression of ER-α is very low in normal colorectal

[HTML][HTML] Estrogens, cancer and immunity

I Orzołek, J Sobieraj, J Domagała-Kulawik - Cancers, 2022 - mdpi.com
Estrogen receptors belong to the family of transcription factors and act by … as a possible value
in colorectal cancer prevention [58]. … of ERs was reported in lung adenocarcinoma [60,61]. …