Findings made in gene panel to whole genome sequencing: data, knowledge, ethics–and consequences?

EC Winkler, S Wiemann - Expert review of molecular diagnostics, 2016 - Taylor & Francis
… However, a number of technical and ethical issues … of genomic science and privacy issues
and agree to forgo the privacy and confidentiality of their genomic data and personal health

Opening Pandora's box?: ethical issues in prenatal whole genome and exome sequencing

R Horn, M Parker - Prenatal diagnosis, 2018 - Wiley Online Library
… Funding sources: The researchethical issues arising in the use of genomic approaches
to prenatal testing. Although there is a sizable literature on prenatal genetics, that on genomics

Ethical and psychosocial issues in whole-genome sequencing for newborns

JD Lantos - Clinical applications for next-generation sequencing, 2016 - Elsevier
Ethical concerns about WGS mirror many of the concerns that have … genomic information
and genome-based health interventions are safe and effective, we need to study their impact on …

[HTML][HTML] Whole-genome sequencing in healthy people

NM Lindor, SN Thibodeau, W Burke - Mayo Clinic Proceedings, 2017 - Elsevier
… Little research has been conducted in this area. We examine the considerable unresolved
scientific and ethical issues encountered when considering whole-genome sequencing of …

Whole-genome sequencing as a method of prenatal genetic diagnosis: Ethical issues

FJ González-Melado - Clinical Ethics At the Crossroads of Genetic and …, 2023 - Elsevier
… as the future applications of WGS. Second, we will explore the ethical implications of adopting
WGS … We believe that it is moral to do research in order to find genetic markers that would …

Genome sequencing guide: An introductory toolbox to wholegenome analysis methods

AN Burian, W Zhao, TW Lo… - … and Molecular Biology …, 2021 - Wiley Online Library
study to apply technical and ethical concepts from the text. … the peril associated with genome
sequencing techniques. This … methods, and socio-ethical issues associated with genome

Whole genome sequencing and its applications in medical genetics

J Wu, M Wu, T Chen, R Jiang - Quantitative Biology, 2016 - Wiley Online Library
… in medical genetics. We highlight the impact of whole genome sequencing in cancer studies,
regulatory variant analysis, predictive medicine and precision medicine, as well as discuss …

Practices and views of neurologists regarding the use of whole-genome sequencing in clinical settings: a web-based survey

I Jaitovich Groisman, T Hurlimann, A Shoham… - European Journal of …, 2017 - nature.com
… and/or ethical issues linked to the current state of knowledge, research and practice …
and perspectives on: (1) clinical practices with genetic/genomic testing (including WGS); (2) …

Views of American OB/GYNs on the ethics of prenatal wholegenome sequencing

MJ Bayefsky, A White, P Wakim, SC Hull… - Prenatal …, 2016 - Wiley Online Library
ethical issues surrounding PWGS and their preparedness for counseling patients on its use.
… However, as our research demonstrates, OB/GYNs' ethical concerns with PWGS are likely to …

Participants and study decliners' perspectives about the risks of participating in a clinical trial of whole genome sequencing

JO Robinson, TM Carroll… - … Research Ethics, 2016 - journals.sagepub.com
… Although the initial plan is to genotype individuals due to budget constraints, eventually
the goal is to perform whole genome sequencing (WGS). In preparation for this study, the …