… Here, we review some established and more recent … mutation status rather than disease
origin. UC San Diego Moores … of this panel outside of ERBB2 in breast cancer is uncertain. …

… Breast cancers can have up to 50 copies of the ERBB2 gene. Increased growth factor receptor
… characterize a breast abnormality, breast MR imaging can be used to evaluate whether a …

… , ERBB2 amplification is a known driver of BC, and so the amplification of NF1 in sporadic
BCs might simply be a function of the two genes being linked on chromosome 17. … review of …

… : “breast carcinoma in situ genetics,” “breast carcinoma in situ … the number and pattern of
genetic abnormalities. Thus, low-… grades, hormone receptor and ERBB2 status, and to identify …

… a breast cancer patient positive for HER2 gene amplification (… satellite centromeric region of
chromosome 17 (D17Z1, CEN17… In the samples included in this study ERBB2 (HER2) status …

… congenital anomalies,22, 23, 24 and a detailed evaluation and … amplification of ERBB2
gene loci on chromosome (Chr) 17 is … picture indicate gross loss or gain of the chromosome 17 …

… of female breast cancer and 31 cases of male breast cancer in … as ErbB2, is overexpressed
in 15-20% of breast cancer … in proximity to the HER2 gene on chromosome 17. The same …

… of specific criteria for the evaluation of HER2 amplification in … using an anti-c-erbB2 antibody
[18] to detect HER2 protein … , including breast cancer, except for one male patient with a …

… of a second primary breast cancer and avoid radiation therapy. … the evaluation that led to the
diagnosis) are recommended. … ERBB2 (previously known as Her2) amplified breast cancers …

… ERBB2 and genes in the ERBB2 amplicon at 17q22.24, … Receptor status is a critical
assessment for all breast cancers … the TP53 gene located on the short arm of chromosome 17 …