[HTML][HTML] Growth factors, PI3K/AKT/mTOR and MAPK signaling pathways in colorectal cancer pathogenesis: where are we now?

C Stefani, D Miricescu, II Stanescu-Spinu… - International journal of …, 2021 - mdpi.com
… will support cancer cell proliferation, survival, motility, and invasion [82]… signaling pathway
plays a crucial role in tumorigenesis, including cancer cell proliferation, migration, and invasion

[HTML][HTML] The Hippo signaling pathway: an emerging anti-cancer drug target

Y Tao, F Cai, L Shan, H Jiang, L Ma… - Discovery …, 2017 - discoverymedicine.com
potential anti-cancer drugs that target components of the Hippo pathway or regulate
interactions between the Hippo signaling pathway and other signaling … , drugs targeting the key

Targeting signalling pathways in hepatocellular carcinoma

K Blagotinsek, D Rozman - Current pharmaceutical design, 2017 - ingentaconnect.com
… in growth signals, insensitivity to growth-inhibitory (anti-growth) signals, evasion of programmed
… is highly conserved through evolution and exerts a crucial role in cancer progression, …

[PDF][PDF] Crossroads of hallmarks in aging and cancer: Anti-aging and anti-cancer target pathways can be shared

K Honoki, H Fujii, S Tsukamoto, S Kishi, T Tsujiuchi… - Tre Can …, 2016 - researchgate.net
… in cancer and aging, namely genetic instability, sustained … signaling/loss of proteostasis,
evading anti-growth signaling/… of cancer cells to proliferate is an important character in cancer

Cancer Development and Progression and the “Hallmarks of Cancer

D Mazingi, K Lakhoo - Pediatric Surgical Oncology, 2023 - Springer
… from growth signals, insensitivity to anti-growth signals, tissue … replicative potential, sustained
angiogenesis, and evasion of … of invasion and metastases or the treatment thereof is a key

[HTML][HTML] Angiogenesis: managing the culprits behind tumorigenesis and metastasis

AHS Yehya, M Asif, SH Petersen, AV Subramaniam… - Medicina, 2018 - mdpi.com
… which is critical for cell proliferation and signalling in tumor … proliferation, neovascularization,
invasion and migration of … Anti-growth factors will probably help to treat angiogenesis …

[HTML][HTML] Angiogenesis-related functions of Wnt signaling in colorectal carcinogenesis

A Kasprzak - Cancers, 2020 - mdpi.com
… , which is a key event in cancer cell dissemination and … potential of cancer, downregulating
angiogenesis, invasion, EMT, … (anti-growth, stimulating cell death) effect on cancer cells [97]. …

[HTML][HTML] Tumor microenvironment and immune evasion in head and neck squamous cell carcinoma

A Elmusrati, J Wang, CY Wang - International journal of oral science, 2021 - nature.com
… This review provides a recent insight into the role of the key … to anti-growth signals, self-sufficiency
in growth signals, … correlated with invasion, cancer relapse, treatment resistance, and …

The tumorigenic effect of sphingosine kinase 1 and its potential therapeutic target

X Wang, Y Sun, X Peng, SMAS Naqvi… - Cancer …, 2020 - journals.sagepub.com
… , 58-60 and Sph is an anti-growth signaling molecule. In contrast, S1P … The SPHK1/S1P
signaling plays a crucial role in … migration and invasion with viral infection as an important factor, …

Adhesion GPCRs in tumorigenesis

G Aust, D Zhu, EG Van Meir, L Xu - Adhesion G protein-coupled receptors …, 2016 - Springer
… migration and invasion toward serum in a breast cancer cell line (… ], but the role of these
signaling events in cancer has not been … It is possible that GPR56 has both pro- and anti-growth