[HTML][HTML] Evidence for Arrhythmogenic Effects of A2A-Adenosine Receptors
P Boknik, K Drzewiecki, J Eskandar, U Gergs… - Frontiers in …, 2019 - frontiersin.org
… of A 2A -ARs increases the susceptibility to arrhythmias in our recently … Furthermore, we
studied the functional role of A 2A -AR … Our results provide evidence for a contractile effect of the …
studied the functional role of A 2A -AR … Our results provide evidence for a contractile effect of the …
Adenosine A2A receptor as potential therapeutic target in neuropsychiatric disorders
MR Domenici, A Ferrante, A Martire, V Chiodi… - Pharmacological …, 2019 - Elsevier
… adenosine binds to the high affinity A 1 and A 2A receptors, but … , the low affinity A 2B and
A 3 receptor are also stimulated [2]. … , epidemiological evidence supports a beneficial role of …
A 3 receptor are also stimulated [2]. … , epidemiological evidence supports a beneficial role of …
Potential Therapeutic Applications of Adenosine A2A Receptor Ligands and Opportunities for A2A Receptor Imaging
A van Waarde, RAJO Dierckx, X Zhou… - Medicinal Research …, 2018 - Wiley Online Library
… levels of extracellular adenosine in the brain are low (in the 10 … The tracer is susceptible to
photoisomerization and human … These data were interpreted as evidence for exercise-induced …
photoisomerization and human … These data were interpreted as evidence for exercise-induced …
Pathological overproduction: the bad side of adenosine
… This model supports the evidence that, at high concentrations, A2A receptor antagonists exert
the … has been found in HD striatum where D1 plus A2A receptor antagonists reduced PKA …
the … has been found in HD striatum where D1 plus A2A receptor antagonists reduced PKA …
[HTML][HTML] The role of adenosine receptors in psychostimulant addiction
… bulb, while A 2B and A 3 receptors are found at low levels of expression. In addition, AR are
… changes in relapse susceptibility. Evidence for the role of A 2A receptors in psychostimulant-…
… changes in relapse susceptibility. Evidence for the role of A 2A receptors in psychostimulant-…
How does adenosine control neuronal dysfunction and neurodegeneration?
RA Cunha - Journal of neurochemistry, 2016 - Wiley Online Library
… the hurdle to undergo degeneration (decreased A 1 R). … methodologies with sufficient
sensitivity and spatiotemporal … the accumulating evidence showing that A 2A R are involved in the …
sensitivity and spatiotemporal … the accumulating evidence showing that A 2A R are involved in the …
Adenosine receptors: Modulators of lipid availability that are controlled by lipid levels
A Leiva, E Guzman-Gutierrez… - Molecular Aspects of …, 2017 - Elsevier
… reviews the evidence showing the mechanism of adenosine/… Finally, we propose a possible
role for adenosine/ARs in the … reduced number of receptors at the cell surface mediated by …
role for adenosine/ARs in the … reduced number of receptors at the cell surface mediated by …
[HTML][HTML] A2B Adenosine Receptor and Cancer
ZG Gao, KA Jacobson - International journal of molecular sciences, 2019 - mdpi.com
… There is growing evidence that the A 2B AR plays an important role in tumor cell … ), reduced
A 2B AR signaling in the glioblastoma, to decrease pathogenesis and increase sensitivity to …
A 2B AR signaling in the glioblastoma, to decrease pathogenesis and increase sensitivity to …
Adenosine receptors in modulation of central nervous system disorders
H Choudhury, DK Chellappan… - Current …, 2019 - ingentaconnect.com
… of A2A ARs is also evidenced in the most susceptible … Literature evidence showed the potential
of adenosine targeting which is … Reduced striatal adenosine A2A receptor levels define a …
of adenosine targeting which is … Reduced striatal adenosine A2A receptor levels define a …
[HTML][HTML] Increased ATP Release and Higher Impact of Adenosine A2A Receptors on Corticostriatal Plasticity in a Rat Model of Presymptomatic Parkinson's Disease
FQ Gonçalves, FC Matheus, HB Silva, JI Real… - Molecular …, 2023 - Springer
… There is robust evidence that A 2A R antagonism attenuates … ) set at 250/ − 175 mV for a
sensitivity at 0.5 nA/V and the peak … Since PPADS has a low efficiency to antagonize P2X4R and …
sensitivity at 0.5 nA/V and the peak … Since PPADS has a low efficiency to antagonize P2X4R and …