Antidepressants promote formation of heterocomplexes of dopamine D2 and somatostatin subtype 5 receptors in the mouse striatum
K Szafran-Pilch, A Faron-Górecka, M Kolasa… - Brain Research …, 2017 - Elsevier
… receptors heterodimers. These findings provide interesting evidence that dopamine D2 and
somatostatin Sst5 heterodimers may be considered as potential mediators of antidepressant …
somatostatin Sst5 heterodimers may be considered as potential mediators of antidepressant …
Somatostatin, a presynaptic modulator of glutamatergic signal in the central nervous system
A Pittaluga, A Roggeri, G Vallarino… - International Journal of …, 2021 - mdpi.com
… innervating the septum, the striatum, the hippocampus and the … somatostatin immunoreactivity
was high, the sst2 receptors … evidence was published demonstrating that somatostatin …
was high, the sst2 receptors … evidence was published demonstrating that somatostatin …
A role for the neuropeptide somatostatin in the neurobiology of behaviors associated with substances abuse and affective disorders
SL Robinson, TE Thiele - Neuropharmacology, 2020 - Elsevier
… We further summarize evidence of a direct role for the SST … observed in this study was
mediated by an increase in CeA SST … infusion increases striatal dopamine release via presynaptic …
mediated by an increase in CeA SST … infusion increases striatal dopamine release via presynaptic …
Regulation of somatostatin receptor 2 in the context of antidepressant treatment response in chronic mild stress in rat
A Faron-Górecka, M Kuśmider, J Solich, M Kolasa… - …, 2018 - Springer
… R in the stress response, we decided to examine the role of sst 2 … role of stress in the levels
of DA in the PFc and striatum, with a … , providing further evidence that this group is overactive. …
of DA in the PFc and striatum, with a … , providing further evidence that this group is overactive. …
Functional mapping of somatostatin receptors in brain: in vivo microdialysis studies
A Kastellakis, J Radke, K Thermos - In Vivo Neuropharmacology and …, 2017 - Springer
… further evidence suggesting that the sst 2 receptor is … showing that the sst 1 receptor mediates
the inhibitory actions of … This study [82] provided conclusive evidence to support that the …
the inhibitory actions of … This study [82] provided conclusive evidence to support that the …
Somatostatin receptor subtype 4 activation is involved in anxiety and depression-like behavior in mouse models
… 2), which provides evidence that separate breeding does not … by the sst 2 receptor activation,
because only the sst 2 agonist … hippocampal somatostatin sst 3 and sst 4 receptors mediate …
because only the sst 2 agonist … hippocampal somatostatin sst 3 and sst 4 receptors mediate …
Clinical significance of filamin A in patients with acromegaly and its association with somatostatin and dopamine receptor profiles
MCA Coelho, ML Vasquez, LE Wildemberg… - Scientific Reports, 2019 - nature.com
… sst2 expression, sst5 expression, dopamine receptor subtype-2 (D2) expression, somatostatin
receptor … , where it acts as a key mediator of cytoskeleton reorganization 11 . FLNA binds …
receptor … , where it acts as a key mediator of cytoskeleton reorganization 11 . FLNA binds …
Structure and Function of Somatostatin and its Receptors in Endocrinology
B Zhang, L Xue, ZB Wu - Endocrine Reviews, 2024 - academic.oup.com
… with the sst2 somatostatin receptor and is an essential component of sst2-mediated inhibitory
… Selective regulation of somatostatin receptor subtype signaling: evidence for constitutive …
… Selective regulation of somatostatin receptor subtype signaling: evidence for constitutive …
Somatostatin and Neurotensin Systems in Schizophrenia
A Induni, F Gil Zbinden, MG López Ordieres - Psychiatry and Neuroscience …, 2021 - Springer
… receptors mediate the inhibition of insulin secretion, and the sst2 receptor seems to mediate
… a culture of dopaminergic neurons, it has been enabled to prove a bidirectional interaction …
… a culture of dopaminergic neurons, it has been enabled to prove a bidirectional interaction …
Somatostatin peptide signaling dampens cortical circuits and promotes exploratory behavior
We sought to characterize the unique role of somatostatin (SST) in the prelimbic (PL) cortex
in mice. We performed slice electrophysiology in pyramidal and GABAergic neurons to …
in mice. We performed slice electrophysiology in pyramidal and GABAergic neurons to …