[HTML][HTML] Staphylococcus aureus adaptive evolution: Recent insights on how immune evasion, immunometabolic subversion and host genetics impact vaccine …

T Wong Fok Lung, LC Chan, A Prince… - Frontiers in Cellular …, 2022 - frontiersin.org
Frontiers | Staphylococcus aureus adaptive evolution: Recent insights on how immune
evasion, immunometabolic subversion and host genetics impact vaccine development Skip to …

Staphylococcus aureus and atopic dermatitis: a complex and evolving relationship

JA Geoghegan, AD Irvine, TJ Foster - Trends in microbiology, 2018 - cell.com
Staphylococcus aureus is frequently isolated from the skin of atopic dermatitis (AD) patients
during flares. The normal microbiota is disrupted and the diversity of the microorganisms on …

[HTML][HTML] Allergy—A New Role for T Cell Superantigens of Staphylococcus aureus?

…, F Schmiedeke, C Bachert, BM Bröker, S Holtfreter - Toxins, 2020 - mdpi.com
Staphylococcus aureus superantigens (SAgs) are among the most potent T cell mitogens
known. … SAgs have evolved in parallel not only in different bacteria but also in viruses; the most …

Bovine Staphylococcus aureus superantigens stimulate the entire T cell repertoire of cattle

GJ Wilson, SW Tuffs, BA Wee, KS Seo… - Infection and …, 2018 - Am Soc Microbiol
… Remarkably, we discovered that some strains have evolved the capacity to stimulate the
entire T cell repertoire of cattle through an array of diverse SAgs, suggesting a key role in …

[HTML][HTML] Manipulation of innate and adaptive immunity by staphylococcal superantigens

SW Tuffs, SMM Haeryfar, JK McCormick - Pathogens, 2018 - mdpi.com
Staphylococcal superantigens (SAgs) constitute a family of potent exotoxins secreted by
Staphylococcus aureus and other select staphylococcal species. … to the evolutionary fitness of S. …

[HTML][HTML] Superantigens, a paradox of the immune response

S Noli Truant, DM Redolfi, MB Sarratea, EL Malchiodi… - Toxins, 2022 - mdpi.com
Staphylococcus aureus, causing multiple affections. This review summarizes the current
knowledge on every superantigen … Microorganisms evolve to evade the host immune system. All …

The evolutionary genomics of host specificity in Staphylococcus aureus

M Matuszewska, GGR Murray, EM Harrison… - Trends in …, 2020 - cell.com
… Genomic and epidemiological studies show that S. aureus has jumped between host species
many times over its evolutionary history. These jumps have involved the dynamic gain and …

Superantigens promote Staphylococcus aureus bloodstream infection by eliciting pathogenic interferon-gamma production

SW Tuffs, MI Goncheva, SX Xu… - Proceedings of the …, 2022 - National Acad Sciences
… that the superantigens (SAgs) are important virulence factors produced during severe
Staphylococcus aureus–… aureus has evolved to take advantage of a human immune system …

[HTML][HTML] The Staphylococcus aureus CC398 Lineage: An Evolution Driven by the Acquisition of Prophages and Other Mobile Genetic Elements

F Laumay, H Benchetrit, AR Corvaglia… - Genes, 2021 - mdpi.com
… The purpose of this short review is to present the main studies of evolution of the S. aureus
… were also devoid of superantigens (enterotoxin and tst genes). Of note, the prevalence of …

Identification and characterization of two novel superantigens among Staphylococcus aureus complex

DF Zhang, XY Yang, J Zhang, X Qin, X Huang… - International Journal of …, 2018 - Elsevier
… It was demonstrated from these results that SEl26 and SEl27 were characterized to be two
novel SE toxins and some SEs evolved along with the bacteria when the organisms adapted …