New insights into exosome mediated tumor-immune escape: Clinical perspectives and therapeutic strategies

AS Pathania, P Prathipati, KB Challagundla - … (BBA)-Reviews on Cancer, 2021 - Elsevier
exosome-mediated immune suppression in the tumor microenvironment and its role in immune
escape and tumor … on the role of exosomes derived from cancer cells or from cells of the …

[HTML][HTML] Exosomal PD-L1: new insights into tumor immune escape mechanisms and therapeutic strategies

K Zhou, S Guo, F Li, Q Sun, G Liang - Frontiers in Cell and …, 2020 - frontiersin.org
… , and promotion of tumor growth. We also discuss the potential implications of ExoPD-L1 as
a … , and the novel therapeutic strategies combining the inhibition of exosome biogenesis with …

[HTML][HTML] A clinician's guide to cancer-derived exosomes: immune interactions and therapeutic implications

MC Knox, J Ni, A Bece, J Bucci, Y Chin… - Frontiers in …, 2020 - frontiersin.org
… of these normal exosomal pathways may provide … immune evasion is accomplished.
Accumulating evidence indicates that immune-active CDEXs also have the potential to impact

The cancer exosomes: Clinical implications, applications and challenges

Z Tang, D Li, S Hou, X Zhu - International journal of cancer, 2020 - Wiley Online Library
implications and challenges of exosomes in cancer progression, therapy resistance, metastasis
and immune escape, … (ALK) carrier reduced the therapeutic effect of ALK inhibitors. Lobb …

[HTML][HTML] HCC-derived exosomes: critical player and target for cancer immune escape

Q Han, H Zhao, Y Jiang, C Yin, J Zhang - Cells, 2019 - mdpi.com
… of tumor-derived exosomes and their key components in mediating tumor immune escape
during … in order to further understand the mechanism of immune escape involving monocytes. …

Clinical implications of exosomal PD‐L1 in cancer immunotherapy

S Ayala-Mar, J Donoso-Quezada… - Journal of …, 2021 - Wiley Online Library
… as a transmembrane protein in exosomes and have revealed exosomal PD-L1 as a mechanism
of tumor immune escape and immunotherapy resistance. Exosomal PD-L1 suppresses …

[HTML][HTML] The effect of hypoxia-induced exosomes on anti-tumor immunity and its implication for immunotherapy

W Guo, T Qiao, B Dong, T Li, Q Liu, X Xu - Frontiers in Immunology, 2022 - frontiersin.org
… -induced exosomes can also promote tumor immune escape … T cells through breast cancer
cell-derived exosomes, thereby … reversed the immunosuppressive effects of the exosomes (48…

Implications of exosomes as diagnostic and therapeutic strategies in cancer

A Aghebati‐Maleki, S Nami… - Journal of Cellular …, 2019 - Wiley Online Library
… for stromal activity, angiogenesis, increased vascular permeability, and immune evasion. …
to clarify the potential of exosomes for the application in cancer diagnosis and therapy. …

[HTML][HTML] Camouflage strategies for therapeutic exosomes evasion from phagocytosis

N Parada, A Romero-Trujillo, N Georges… - Journal of advanced …, 2021 - Elsevier
… of systemically injected exosomes, hindering their therapeutic effect. Exosomes ‘Camouflage
Cloak… of strategies that promote an immune evasion to increase a longer circulation time of …

Immune escape mediated by exosomal PD‐L1 in cancer

SE Lawler, MO Nowicki, FL Ricklefs… - Advanced …, 2020 - Wiley Online Library
… in tumor tissues. These findings provide further support for the concept … exosomal PD-L1
as a mediator of tumor immune escape. 7 Exosomal PD-L1 Functions in Head and Neck Cancer