… loss of Bcl-2 expression, Bcl-2(-) patients, and low degree of … on breast adenocarcinoma,
where Bcl-2 overexpression was … apoptosis in colorectal cancers with microsatellite instability. …

… decreased mortality risk in CRC patients and Bcl-2 … that expression of the Bcl-2 protein is
associated with favorable prognosis in patients with CRC. Subgroup analysis showed that Bcl-2 …

… involves members of the Bcl-2 protein family. Members of the … specific for microsatellite
unstable (MSI) and microsatellite stable (… results suggest that decreases in the expression of these …

… validated in the TCGA colon adenocarcinoma (COAD) cohort … We further included the age,
sex, stage, microsatellite stable … to BCL-2 antagonists was shown to identify patients with low …

… instability analysis is becoming more and more important in colorectal cancer patients.
The … of colorectal cancer classification and diagnostic features of microsatellite instability. …

… CRC can be classified as adenocarcinoma not otherwise … a significant decrease in expression
of Bcl-2 in normal colorectal … The DNA MMR proteins form part of the basis of microsatellite …

… (BAX) genes encode proteins which cooperate to regulate … the expression levels of EP300,
TP53 and BAX in colorectal cancer (… The average expression of TP53 mRNA was lower in the …

… 17 and BCL-2 levels in the TCGA dataset of micro-satellite stable … supported by the decrease
in BCL-2 expression detected upon … , such a decrease in antiapoptotic protein expression is …

… with colorectal adenocarcinoma. Microsatellite instability (MSI) was performed in 33 primary
… C- HCT116 +miR-15a cells also showed reduced expression levels of BCL-2 in comparison …

… In conclusion, low expression of Bcl‑2 is significantly correlated with advanced pathological
… a significant negative association between Bcl-2 expression and microsatellite instability, as …