… chronic inflammatory diseases: multiple sclerosis (MS), … places CCR7 and its ligands in
control of a central immune hub … suggest that CCR7 participates in memory T cell CNS infiltration …

… Here we report that CCR7 mediates CD11c+ cell migration from the CNS parenchyma to
the … Expression of CCR7 in multiple sclerosis: implications for CNS immunity. Annals of …

… Multiple sclerosis (MS) is the most common chronic … surveillance in the healthy CNS and for
immune trafficking in MS … Based on these findings and the description of expression of CCR7 …

… and immune activation, and are important in immunity and … CCR7 migrates naive T cells and
central memory T cells to … , CCL5 is significantly expressed in the CNS during acute disease, …

… 7 (CCR7) is expressed in both CNS resident cells and peripheral … C chemokine receptor 7
(CCR7) – an immune molecule we propose … Multiple sclerosis (MS) is an autoimmune disease …

… direct effects on the central nervous system (CNS) [14–17]. … T cells expressing lymph
node-homing receptors such as CCR7. … We defined a t test significance threshold (p value <0.001) …

… Multiple sclerosis (MS) is a neurodegenerative and immune-… enhanced CCr7 and reduced
CD206 expression compared … infiltration immune-cells into the central nervous system [7]. The …

… inflammatory disorder of the CNS is multiple sclerosis (MS), … of the CNS has been coined an
immune-privileged site … lymphoid tissues by expressing homing markers CCR7 and CD62L, …

… demyelinating disease of the central nervous system (CNS). However, … High expression of
CCL20 has been demonstrated in the … Our data have important implications not only for our …

… of CNS immune surveillance, as well as multiple sclerosis … In our data, CCR7 was
significantly downregulated in CSF … The aetiological significance of observed gene expression …