CRISPR Element Patterns vs. Pathoadaptability of Clinical Pseudomonas aeruginosa Isolates from a Medical Center in Moscow, Russia

M Tyumentseva, Y Mikhaylova, A Prelovskaya… - Antibiotics, 2021 - mdpi.com
… a high plasticity and spacer … We identified the virulence factors in the clinical isolates
investigated by a bioinformatics analysis of WGS data. The complete list of detected virulence genes

Beyond the pan-genome: current perspectives on the functional and practical outcomes of the distributed genome hypothesis

JA Hammond, EA Gordon, KM Socarras… - Biochemical Society …, 2020 - portlandpress.com
clinical isolates (of each of their respective species) revealed … , the number of novel genes
identified with each additional … and Pseudomonas aeruginosa the relative size of the core …

A Site-Specific Integrative Plasmid Found in Pseudomonas aeruginosa Clinical Isolate HS87 along with A Plasmid Carrying an Aminoglycoside-Resistant Gene

D Bi, Y Xie, C Tai, X Jiang, J Zhang, EM Harrison, S Jia… - PloS one, 2016 - journals.plos.org
… at the tRNA Thr locus was identified on the chromosome of P. … Moreover, many resistance
plasmids are being detected in P… the plasticity of the genome and has potential to serve as a …

Phylogenomic analysis of Clostridioides difficile ribotype 106 strains reveals novel genetic islands and emergent phenotypes

BAP Roxas, JL Roxas, R Claus-Walker… - Scientific Reports, 2020 - nature.com
… difficile ribotype frequency distribution, particularly the … Our clinical isolates are designated
as “GV”, whereas … segment occurs in the same gene order but with some sequence plasticity

Pan-genome analysis of Delftia tsuruhatensis reveals important traits concerning the genetic diversity, pathogenicity, and biotechnological properties of the species

Z Yin, X Liu, C Qian, L Sun, S Pang, J Liu… - Microbiology …, 2022 - Am Soc Microbiol
… tsuruhatensis and revealed extensive genetic diversity and genetic plasticity exhibited by …
aeruginosa MDR clinical isolate (15). Hence, the distribution, genetic backgrounds, and …

Pseudomonas aeruginosa and microbial keratitis

Y Hilliam, S Kaye, C Winstanley - Journal of medical …, 2020 - microbiologyresearch.org
… of genomic plasticity (RGP) at specific sites on the genome, which … It showed that rates of
resistance in ocular isolates of P. … aeruginosa clinical isolates [76]. When tested alone, the most …

Genome plasticity as a paradigm of antibiotic resistance spread in ESKAPE pathogens

S Das, S Bombaywala, S Srivastava, A Kapley… - … and Pollution Research, 2022 - Springer
… baumannii, Pseudomonas aeruginosa and Enterobacter spp.) … found to be core ARGs
distributed throughout the genome in … study showed pMW2 (rep5) plasmid carrying blaZ among

Comparative Genomic Analysis Reveals Genetic Mechanisms of the Variety of Pathogenicity, Antibiotic Resistance, and Environmental Adaptation of Providencia …

C Yuan, Y Wei, S Zhang, J Cheng, X Cheng… - Frontiers in …, 2020 - frontiersin.org
… from clinical isolates were sequenced for pan-genome … In summary, the differential distribution
of virulence-related genegenomes exhibited high levels of evolutionary plasticity, with …

No Correlation between Biofilm Formation, Virulence Factors, and Antibiotic Resistance in Pseudomonas aeruginosa: Results from a Laboratory-Based In Vitro Study

M Gajdács, Z Baráth, K Kárpáti, D Szabó, D Usai… - Antibiotics, 2021 - mdpi.com
… due to its pronounced genomic plasticity and rich resistome, it … of the isolates, respectively,
with clinical isolates having higher … Our study has showed that isolates with the MDR and non-…

[HTML][HTML] Comparative genomic analysis of Staphylococcus haemolyticus reveals key to hospital adaptation and pathogenicity

M Pain, E Hjerde, C Klingenberg… - Frontiers in …, 2019 - frontiersin.org
… In the clinical isolates, we commonly identified a homolog of the … We identified a large
number of IS elements, ranging from 15 … (B) Pie chart showing the distribution of all identified CP …