… Accordingly, scavengers of intracellular ROS are capable of … arrest calcium mobilization, ATP
release and platelet aggregation… , inhibition of mitophagy, either from chemical inhibition or …

… can swiftly dedifferentiate and return to the proliferating stage … In this in vitro model and in ex
vivo in organotypic murine … response of Schwann cells including migration, proliferation, and …

… Additionally, we have used the ex vivo skinnerve preparation to characterize the role of …
distal or Wallerian degeneration, myelin and Remak cells go through dedifferentiation to …

… After axotomy, the distal axon undergoes Wallerian degeneration … by Schwann cells, induces
Schwann cells dedifferentiation … the AKT is an inhibitor of axon degeneration after axotomy. …

… and reduced Schwann cell proliferation during development in … the degenerative phase
of Wallerian degeneration (WD) and … Our results indicate that dedifferentiated Schwann cells …

… effect of JNK and NRAGE inhibition in cultured SCG neurons … process, which includes
Wallerian degeneration (breakdown of … , while satellite glial cells and Schwann cells reside in the …

… -α) was used to induce dedifferentiation of primary rat spinal … to oligodendrocyte lineage cells,
inhibited astrogliosis, promoted … die after SCI, while reactive astrocytes begin to proliferate. …

… We first confirmed that the virus highly transduced Schwann cells and that AAV9 shRNA …
cytoskeleton and extracellular matrix ...... 56 4. Upregulation of Schwann cells differentiation …

… inhibit fusion of autophagosomes with lysosomes, the cells … and demyelination by an ex
vivo approach to investigate … Schwann cells resulted in Schwann cell dedifferentiation and …