C-terminal domain phosphatase-like 1 (CPL1) is involved in floral transition in Arabidopsis

C Yuan, J Xu, Q Chen, Q Liu, Y Hu, Y Jin, C Qin - BMC genomics, 2021 - Springer
… of processing primary miRNAs into mature miRNAs in plants is … We then analyzed CPL protein
sequence of Arabidopsis and other different … CPL1 is a phosphatase that can regulate the …

The protein phosphatase 4 and SMEK1 complex dephosphorylates HYL1 to promote miRNA biogenesis by antagonizing the MAPK cascade in Arabidopsis

C Su, Z Li, J Cheng, L Li, S Zhong, L Liu, Y Zheng… - Developmental Cell, 2017 - cell.com
… Phosphorylation plays an essential role in microRNA (miRNA) processing by regulating
co-factors … KH domain protein RCF3 is a tissue-biased regulator of the plant miRNA biogenesis …

Regulation of pri-MIRNA processing: mechanistic insights into the miRNA homeostasis in plant

J Jodder - Plant Cell Reports, 2021 - Springer
CPL phosphatases are a group of processing factors which can regulate the activity of … HYL1
can interact with DCL1 and thus promote the pri-MIRNA processing (Manavella et al. 2012). …

A quick HYL1-dependent reactivation of microRNA production is required for a proper developmental response after extended periods of light deprivation

NP Achkar, SK Cho, C Poulsen, AL Arce, DA Re… - Developmental cell, 2018 - cell.com
Fast-forward genetics identifies plant CPL phosphatases as regulators of miRNA
processing factor HYL1. … Fast-forward genetics identifies plant CPL phosphatases as …

Regulation of plant microprocessor function in shaping microRNA landscape

J Dolata, M Taube, M Bajczyk, A Jarmolowski… - Frontiers in Plant …, 2018 - frontiersin.org
… complexes and negatively affect pri-miRNA processing. Arabidopsis mutant in debranching
… Beside phosphatases, kinases have also been found to be important for HYL1 phospho-…

The plant FYVE domain‐containing protein FREE1 associates with microprocessor components to repress miRNA biogenesis

H Li, T Li, Y Li, H Bai, Y Dai, Y Liao, J Wei, W Shen… - EMBO …, 2023 - embopress.org
… as a negative regulator of miRNA biogenesis and provides … In this screen, we identified
clones encoding a phosphatase CPL1 (… in miRNA processing, FREE1 is a negative regulator for …

HASTY modulates miRNA biogenesis by linking pri-miRNA transcription and processing

DA Cambiagno, AJ Giudicatti, AL Arce, D Gagliardi… - Molecular plant, 2021 - cell.com
… -transcriptional gene regulation during both development and stress responses in plants
( … Importantly, we found that HST is not directly involved in pri-miRNA processing, as is its …

Recent advances in the regulation of plant miRNA biogenesis

M Li, B Yu - RNA biology, 2021 - Taylor & Francis
… To date, hundreds of miRNAs have been identified in plants. These … involved in miRNA
processing and ribonucleases, which provide a new regulatory layer of miRNA biogenesis. …

miRNA biogenesis: a dynamic pathway

NP Achkar, DA Cambiagno, PA Manavella - Trends in Plant Science, 2016 - cell.com
… of the dynamic regulation of miRNA biogenesis. We put special … Supporting this idea, C-TERMINAL
DOMAIN PHOSPHATASE-… that CPL proteins are also recruited into the processing

Structural determinants in the miRNA/miRNA* duplex and the DCL1 PAZ domain for precise and efficient plant miRNA processing

H Zhang, F Li - The Plant Journal, 2024 - Wiley Online Library
… Other factors that may regulate miRNA processing precision and accumulation levels are not
well studied… Key residues in the DCL1 PAZ domain were identified that form the predicted 3 …