Preclinical models for obesity research
P Barrett, JG Mercer, PJ Morgan - Disease models & …, 2016 - journals.biologists.com
… This diet and feeding regime resulted in increases in body fat … the ability to assess dietary
preference and to quantify choice … orexigenic peptides such as galanin, dynorphin and …
preference and to quantify choice … orexigenic peptides such as galanin, dynorphin and …
Wiring the Brain for Wellness: Sensory Integration in Feeding and Thermogenesis: A Report on Research Supported by Pathway to Stop Diabetes
CE Riera - Diabetes, 2024 - Am Diabetes Assoc
… an essential role in the short-term regulation of feeding by … upon high-fat diet feeding (61).
This research showed that … hyperphagia and behaviors resembling binge eating in rodent …
This research showed that … hyperphagia and behaviors resembling binge eating in rodent …
[HTML][HTML] Drastic decline in vasoactive intestinal peptide expression in the suprachiasmatic nucleus in obese mice on a long-term high-fat diet
D Afonso-Oramas, L Santana-Cordón… - Brain Research …, 2023 - Elsevier
… , these mice had an altered circadian feeding behaviour. … In this work, our results conclude
that VIP plays a crucial role … obese mice subjected to an obesogenic diet, which is supported …
that VIP plays a crucial role … obese mice subjected to an obesogenic diet, which is supported …
Presynaptic regulation of leptin in a defined lateral hypothalamus–ventral tegmental area neurocircuitry depends on energy state
… excessive storage of energy by high-fat diet feeding dampen the suppressive effect of leptin
on … The less preferred compartment was subsequently paired with 5 g of 45% kcal/fat diet (…
on … The less preferred compartment was subsequently paired with 5 g of 45% kcal/fat diet (…
Endocannabinoids in body weight control
H Horn, B Böhme, L Dietrich, M Koch - Pharmaceuticals, 2018 - mdpi.com
… in hypothalamic feeding circuitry is further supported by the … This preference is lost in
knockout-mice lacking the CD36 fat … therefore, dietary fat influences our eating habits. Therefore, …
knockout-mice lacking the CD36 fat … therefore, dietary fat influences our eating habits. Therefore, …
Convergence between biological, behavioural and genetic determinants of obesity
S Ghosh, C Bouchard - Nature Reviews Genetics, 2017 - nature.com
… In the meantime, to ensure continued support, we are … traits, for example, hyperphagia and
food preference or a … the role of common SNPs in variations in BMI and body fat percentage, …
food preference or a … the role of common SNPs in variations in BMI and body fat percentage, …
Neural basis of hunger-driven behaviour in Drosophila
S Lin, B Senapati, CH Tsao - Open Biology, 2019 - royalsocietypublishing.org
… Flies change their food preferences in response to lack of … -2 are homologues of the mammalian
galanin receptors [57,58]. … of sptr in fat body has no effect on feeding behaviour. Instead…
galanin receptors [57,58]. … of sptr in fat body has no effect on feeding behaviour. Instead…
The role of the melanocortin system in metabolic disease: new developments and advances
JW Hill, LD Faulkner - Neuroendocrinology, 2017 - karger.com
… that fed mice showed neither an aversion to nor a preference for … Unlike in high-fat diet-induced
obese mice, blood pressure is not … These studies support the hypothesis that MC4Rs in …
obese mice, blood pressure is not … These studies support the hypothesis that MC4Rs in …
[PDF][PDF] The role of zinc in the endocrine system.
… , protein-carbohydrate-lipid metabolism, immune system, wound … Zinc deficiency changes
preferred macronutrient intake in … feeding behaviour and changes in hypothalamic galanin and …
preferred macronutrient intake in … feeding behaviour and changes in hypothalamic galanin and …
Circadian rhythms of the hypothalamus: from function to physiology
R Van Drunen, K Eckel-Mahan - Clocks & sleep, 2021 - mdpi.com
… from adipose tissue, and regulates diurnal feeding rhythms … This is likely due in part to
changes in galanin- and GABA-… -PVN neurons to induce preference for carbohydrates lays the …
changes in galanin- and GABA-… -PVN neurons to induce preference for carbohydrates lays the …