Recent advances of pharmaceutical crystallization theories

J Weng, Y Huang, D Hao, Y Ji - Chinese Journal of Chemical Engineering, 2020 - Elsevier
… of crystallization is still rare, and the control of crystallizationpharmaceutical crystallization
filed and review advances in the research on the theories of pharmaceutical crystallization

Recent Advances in the Application of Machine Learning to Crystal Behavior and Crystallization Process Control

M Lu, S Rao, H Yue, J Han, J Wang - Crystal Growth & Design, 2024 - ACS Publications
pharmaceuticals and advancements in material science. To anticipate crystal behavior and
pinpoint effective crystallization … model over a first-principles model is that crystallization is a …

Recent progress in continuous crystallization of pharmaceutical products: precise preparation and control

Y Ma, S Wu, EGJ Macaringue, T Zhang… - … Process Research & …, 2020 - ACS Publications
crystalline pharmaceutical products, so selecting a suitable continuous crystallizer is a
prerequisite for precise control of the pharmaceutical-related crystalline … ) presented first-principles

[HTML][HTML] Application of PAT-based feedback control approaches in pharmaceutical crystallization

Y Gao, T Zhang, Y Ma, F Xue, Z Gao, B Hou, J Gong - Crystals, 2021 - mdpi.com
… Based on the current progress of pharmaceutical crystallization process control, this paper
… of industrial crystallization process control through process analysis technology and control

Firstprinciples modeling of molecular crystals: structures and stabilities, temperature and pressure

J Hoja, AM Reilly, A Tkatchenko - Wiley Interdisciplinary …, 2017 - Wiley Online Library
… that find applications as pharmaceuticals, explosives, organic … crystalline phase diagram
calculated from first principles. This … In addition, we would like to explicitly include crystallization

Application of model-free and model-based quality-by-control (QbC) for the efficient design of pharmaceutical crystallization processes

B Szilagyi, A Eren, JL Quon… - … Growth & Design, 2020 - ACS Publications
… This study presented a comprehensive description for the application of the quality-by-control
(QbC) framework for pharmaceutical crystallization design. QbC has the potential to …

Mechanisms and control of impurities in continuous crystallization: a review

C Darmali, S Mansouri, N Yazdanpanah… - Industrial & …, 2018 - ACS Publications
… fine chemicals and the pharmaceutical and food industries. It is important to strategically …
the purity control in the batch process with the continuous approach to the crystallization. The …

Polymorphic control and scale-up strategy for antisolvent crystallization using a sequential supersaturation and direct nucleation control approach

I Ostergaard, B Szilagyi, HL De Diego, H Qu… - … Growth & Design, 2020 - ACS Publications
direct design approach for crystallization processes was implemented using the novel
Quality-by-Control (… Crystallization is a key unit operation in the pharmaceutical industry and often …

Polymorphic control and scale-up strategy for antisolvent crystallization using direct nucleation control

I Ostergaard, B Szilagyi, HL De Diego, H Qu… - … Growth & Design, 2020 - ACS Publications
… of direct design and quality-by-control (QbC) was applied and investigated using direct
nucleation control (… Crystallization is a key unit operation in the pharmaceutical industry, often …

[图书][B] Pharmaceutical crystals: science and engineering

T Li, A Mattei - 2018 - books.google.com
… three-dimensional (3D) crystal structure, yet it is not given that a drug candidate entering
into pharmaceutical development will crystallize, let alone in a form that is amenable to …