[HTML][HTML] Metabolism and pharmacological activities of the natural health-benefiting compound diosmin

Y Zheng, R Zhang, W Shi, L Li, H Liu, Z Chen, L Wu - Food & function, 2020 - pubs.rsc.org
diosmetin induces apoptosis in renal carcinoma ACHN cells … of flavonoids have been
linked to the inhibition of ATP … , diosmetin may completely reverse the ATP-depleting effects

[HTML][HTML] Comprehensive review on therapeutic and phytochemical exploration of diosmetin: A promising moiety

M Garg, SK Chaudhary, A Goyal, P Sarup, S Kumari… - Phytomedicine …, 2022 - Elsevier
… acids and flavonoids as its active constituents including diosmetin-6-o-… The diosmetin was
found to protect against renal injury in … Diosmetin was able to amplify the ATP production and …

[HTML][HTML] … and diosmetin inhibited the HSP70/TLR4/NF-κB p65/NLRP3 signaling pathways and switched macrophage to M2 phenotype in a rat model of acute kidney …

HM Saad, E Elekhnawy, MA Shaldam… - Biomedicine & …, 2024 - Elsevier
… One of the main flavonoid compounds recently extracted … resulted in a substantial rise in the
renal index by 224% relative … Time-kill curve helps us to understand the possible interactions …

Diosmetin as a promising natural therapeutic agent: In vivo, in vitro mechanisms, and clinical studies

Z Sun, K Liu, C Liang, L Wen, J Wu… - Phytotherapy …, 2024 - Wiley Online Library
Diosmetin (DIO, Figure 2) is a flavonoid compound that can be … the MAPK pathway helps
safeguard cells during oxidative stress. … DIO increased the ATP levels in MDCK kidney cells and …

[HTML][HTML] Diosmetin protects against retinal injury via reduction of DNA damage and oxidative stress

Z Shen, J Shao, J Dai, Y Lin, X Yang, J Ma, Q He… - Toxicology Reports, 2016 - Elsevier
… ) is the aglycone of the flavonoid glycoside diosmetin-7-O-β-d-… enhance the adenosine
triphosphate (ATP) levels in cells [36]… improves eye function based on the analysis of its protective …

… THE MOLECULAR MECHANISMS UNDERLYING THE ANTI-CANCER ACTIVITIES OF DIOSMETIN IN COLORECTAL CANCER CELLS: AN IN VITRO STUDY

SN AHMED - 2022 - qspace.qu.edu.qa
… or the tissue lining of different organs such as the liver, kidneys… OXPHOS), which are required
for adenosine triphosphate (ATP) … Anticancer effects of the flavonoid diosmetin on cell cycle …

[HTML][HTML] Inhibition of TGF-β Signaling in Gliomas by the Flavonoid Diosmetin Isolated from Dracocephalum peregrinum L.

Y Yan, X Liu, J Gao, Y Wu, Y Li - Molecules, 2020 - mdpi.com
… Conclusion: The results of this study suggest that diosmetin suppresses the growth of glioma
cells in vitro and in vivo, possibly by activating E-cadherin expression and inhibiting the TGF…

Overview and Potential Benefits of Flavonoids in Diabetes

S Kabra, AP Singh, V Kesharwani… - Advances in Flavonoids …, 2024 - taylorfrancis.com
… of high cellular energy demand the increase in AMP/ATP is … therapy helps to lower the
blood sugar level that is increased … Prophylactic effect of baicalein against renal dysfunction in …

[PDF][PDF] INTRACELLULAR ACCUMULATION OF QUERCETIN AND ITS IMPACT ON CELLULAR STRESS: AN IN VITRO STUDY

H Criel - 2019 - libstore.ugent.be
… the protective effect of flavonoids against cellular stress in cells, … the flavonoid diosmetin
had no effect on the reduced ATP … Total levels of cellular ATP (adenosine triphosphate) were …

A therapeutic connection between dietary phytochemicals and ATP synthase

Z Ahmad, SS Hassan, S Azim - Current medicinal chemistry, 2017 - ingentaconnect.com
… mechanism generates adenosine triphosphate (ATP) from … decreased ATPase activity in
aging rat kidneys [44]. One of the … Antioxidant activities, total phenolics and flavonoids content in …