[HTML][HTML] Therapeutic role of flavonoids and flavones in cancer prevention: Current trends and future perspectives
… various protein kinases such as cyclin-dependent kinases (… add a phosphate group to
proteins and other molecules. The … 3 kinase) signaling path way by direct inhibition of this protein …
proteins and other molecules. The … 3 kinase) signaling path way by direct inhibition of this protein …
[HTML][HTML] Cancer chemoprevention through dietary flavonoids: what's limiting?
… by inhibiting their metabolism [22,23,24]. The molecular mechanisms by which flavonoids …
), and mitogen-activated protein kinases (MAPK or extracellular signal-related kinase [ERK]) …
), and mitogen-activated protein kinases (MAPK or extracellular signal-related kinase [ERK]) …
[HTML][HTML] Molecular targets of genistein and its related flavonoids to exert anticancer effects
… activated protein kinase (MAPK), phosphoinositide 3-kinase (… that several flavonoids, including
genistein directly inhibit … is a promising compound for cancer prevention and treatment. Its …
genistein directly inhibit … is a promising compound for cancer prevention and treatment. Its …
[HTML][HTML] Compounds from natural sources as protein kinase inhibitors
… In the beginning, small molecule protein kinase inhibitors were … , flavonoids isolated from
plant materials are potential … It has been shown that the compound directly and indirectly affects …
plant materials are potential … It has been shown that the compound directly and indirectly affects …
Acacetin and pinostrobin as a promising inhibitor of cancer-associated protein kinases
… Therefore, cancer prevention/treatment, targeting kinases with phytochemicals could be
a … of selected flavonoids for cancer-chemoprevention/treatment. The molecular docking …
a … of selected flavonoids for cancer-chemoprevention/treatment. The molecular docking …
[HTML][HTML] Exploring the natural compounds in flavonoids for their potential inhibition of cancer therapeutic target MEK1 using computational methods
… natural products for cancer prevention that have been … flavonoids’ inhibition activity
against Ser/The protein kinases … , the molecular docking results suggest that some flavonoids …
against Ser/The protein kinases … , the molecular docking results suggest that some flavonoids …
[HTML][HTML] Targeting PI3K/Akt/mTOR pathway by different flavonoids: a cancer chemopreventive approach
… is the phosphoinositide 3-kinase (PI3K)-protein kinase B (Akt)… Akt directly but modifies Akt
configuration by binding to its PH … -dependent kinase-1 (PDK1) to phosphorylate the kinase …
configuration by binding to its PH … -dependent kinase-1 (PDK1) to phosphorylate the kinase …
[PDF][PDF] A review of significant molecular mechanisms of flavonoids in prevention of prostate cancer
S Ghasemi, Z Lorigooini - J Chem Pharm Sci, 2016 - core.ac.uk
… as a protective factor against cancer. Recent researches have revealed that diets based
on flavonoids have the potential benefits for cancer prevention. Flavonoids are part of a large …
on flavonoids have the potential benefits for cancer prevention. Flavonoids are part of a large …
[PDF][PDF] Flavonoids: Molecular mechanism behind natural chemoprotective behavior-a mini review
… the cell-like protein kinase activity inhibition, spreading of tumor cells, … directly. So, microbe
production of natural products like … new research rationales for cancer prevention. The various …
production of natural products like … new research rationales for cancer prevention. The various …
[HTML][HTML] The hallmarks of flavonoids in cancer
LGS Ponte, ICB Pavan, MCS Mancini, LGS da Silva… - Molecules, 2021 - mdpi.com
… Flavonoids have shown direct effects on glutathione … proto-oncogene serine/threonine-protein
kinase (Raf), and ERK in … -Activated Protein Kinase Kinase 1 (MEK1) inhibitor, leading to …
kinase (Raf), and ERK in … -Activated Protein Kinase Kinase 1 (MEK1) inhibitor, leading to …