… and flutamide, appeared slightly favorable to cancer patient … of prostatic intraepithelial
neoplasia (PIN). This means that … was examined by evaluating the chemopreventive efficacy of …

… general, age-standardised Finnish male population. In the ESKO … 3, randomized, double-blind,
placebo controlled efficacy and … is high-grade intraepithelial neoplasia (HGPIN) [107]. The …

… Pharmacological drugs like flutamide, DFMO, bicalutamide (… study, a large, randomized,
double-blind, placebo-controlled … may progress to prostatic intraepithelial neoplasia and/or …

… such as bicalutamide, nilutamide, and flutamide, were also developed; these anti-androgens …
the first AR NTD inhibitor tested in a Phase 1 study in men with CRPC. The drug was well-…

… tea consumption and cancer chemoprevention in men diagnosed with prostate cancer [1],
[2]… commonly dysregulated in the development of prostate cancer, and could potentially act in …

… Prostate and breast cancer are the two cancers with the highest incidence in men and …
resistance to antihormone therapy of prostate and breast cancer and compare laboratory and …

… Men with localized or regionally spread prostate cancer have … pathway and transforms prostate
epithelial cells [155]. … ) for prostate cancer treatment included bicalutamide, flutamide, and …

… earlier steroidal anti-androgen flutamide, is more commonly … -initiating population of prostate
epithelial cells but upregulated … the FDA in a chemoprevention role for prostate cancer, and …

… Moreover, prostate cancer is ideal for chemoprevention due … its activity was synergic with
flutamide, an antagonist of AR [… towards benign prostate epithelial cells and LNCaP cancer cells …

… in GPE as a chemopreventive and anti-cancer agent against prostate cancer but also
emphasize the … (PCa), it is still the most frequently diagnosed cancer in men in the United States, …