… the mammalian genome that plays critical roles in chromatin structure and gene expression.
… completed with the establishment of sex-specific methylation patterns during later stages of …

… We highlight the dynamic erasure and re-establishment of DNA methylation in … , the
mammalian genome undergoes two extensive waves of reprogramming of CpG methylation patterns …

… including MeCP2, MBD1, or MBD2, which establish strong repression of gene expression
by containing transcriptional repression domains and forming complexes with other silencing …

… sequence compartments that make up the mammalian genome, and we offer an updated
interpretation of the nature of the changes in methylation patterns that occur in germ cells and …

… establishment of DNA methylation patterns specific to each germ cell type or somatic cell type
after the erasure. Once cell type-specific DNA methylation patterns … the pattern throughout …

… DNA to establish DNA methylation patterns, and maintenance methyltransferase(s)
methylate newly formed hemimethylated CpG sites during DNA replication to maintain the …

… of DNA methylation patterns and functions. We show that the chicken genome is hypomethylated
… in the parental gametes and can also direct the establishment of somatic DMRs in the …

… or establishment of DNA methylation, respectively. As a proof of principle, we first induced
alterations to DNA methylation in two synthetic methylation … facilitates myotube formation. With …

… DNA methylation in the mammalian genome and explore the current state of DNA methylation-…
DNMT3A is especially required for the establishment of methylation of imprinted genes in …

… Here we review the roles of DNA methylation in the establishment and maintenance of cell
identity during development, with a special emphasis on insights obtained from in vivo studies…