Topical Corticosteroids and Glucocorticoid-Induced Osteoporosis—Cumulative Dose and Duration Matter

RD Jackson - JAMA dermatology, 2021 - jamanetwork.com
… Conversely, when the cumulative dose of intermittent high-dose glucocorticoids is low (<1
g), the fracture risk is much lower than that reported for doses of 1 g or higher. …

Association of potent and very potent topical corticosteroids and the risk of osteoporosis and major osteoporotic fractures

A Egeberg, P Schwarz, T Harsløf… - JAMA …, 2021 - jamanetwork.com
… Although prolonged, high-dose systemic corticosteroid use causes bone loss and increased
fracture risk, this area has been largely unexplored for TCS use. Previously, a Danish case-…

Association between topical corticosteroid use and fracture risk among pediatric patients with atopic dermatitis

RL Imhof, AL Weaver, JS Sauver, J Hand… - Journal of the American …, 2022 - jaad.org
… Little is known about the risk of fracture in children with AD on topical corticosteroids. The …
association between topical corticosteroid use and subsequent fracture risk among children …

Higher cumulative dose of topical corticosteroids is associated with osteoporosis and major osteoporotic fracture: A nationwide case–control study

BJ Hsieh, D Shen, TC Chan, YT Cho… - Journal of the …, 2024 - Wiley Online Library
Systemic corticosteroids can interfere with bone remodelling and increase osteoporosis
and fracture risk, but evidence on the negative effects of topical corticosteroids (TCSs) on bone …

[HTML][HTML] Effects of systemic glucocorticoid use on fracture risk: a population-based study

JW Koh, J Kim, H Cho, YC Ha, TY Kim… - Endocrinology and …, 2020 - synapse.koreamed.org
… increased risk of osteoporotic fracture [12]. There are several reports of increased risk of
fractures … the dose-dependent fracture risk based on the total amount of systemic GC use among …

[HTML][HTML] Atopic eczema–associated fracture risk and oral corticosteroids: a population-based cohort study

J Matthewman, KE Mansfield, D Prieto-Alhambra… - The Journal of Allergy …, 2022 - Elsevier
… , topical corticosteroids may still explain some of the association between atopic eczema and
fracture risk … severity included prescriptions for topical corticosteroids and may, therefore, to …

Risk and management of osteoporosis due to inhaled, epidural, intra-articular or topical glucocorticoids

AD Anastasilakis, AM Naciu, MP Yavropoulou… - Joint Bone Spine, 2023 - Elsevier
… Similarly, regarding fracture risk, analysis of data from 8 RCTS and 17,686 patients found
similar fracture risk among inhaled GCs (mostly budesonide and in one study fluticasone …

Fracture risks in patients with atopic dermatitis: A nationwide matched cohort study

TL Lin, CY Wu, JJY Yen, CK Juan, YL Chang… - Annals of Allergy …, 2021 - Elsevier
… factors associated with increased fracture risk is unavailable from … of body surface area of
topical corticosteroids are difficult to … from the NHIRD can affect systemic absorption of topical

Implication of topical steroids in the onset of osteoporosis

AA Milyani, AE Al-Agha - Case reports in pediatrics, 2018 - Wiley Online Library
topical steroid therapy be screened for OP with the consideration of instituting prophylactic
treatment especially in those suffering from … bone fracture either in a child known to suffer from

Risk for osteoporosis and fracture with glucocorticoids

M Urquiaga, KG Saag - Best Practice & Research Clinical Rheumatology, 2022 - Elsevier
topical corticosteroids have been associated with an increased risk of osteoporosis and major
osteoporotic fractures … 15% for major osteoporotic fracture and 20% for hip fracture risk, for …