[HTML][HTML] From mouse to man and back: closing the correlation gap between imaging and histopathology for lung diseases

B Tielemans, K Dekoster, SE Verleden, S Sawall… - Diagnostics, 2020 - mdpi.com
… and novel developments in imaging, lung functional testing and pathological techniques …
animal models (mainly rodents) to unravel disease processes in the lung. Although these and …

Multistage self‐gated lung imaging in small rodents

M Tibiletti, Å Kjørstad, A Bianchi… - Magnetic resonance …, 2016 - Wiley Online Library
… , rodent lungs imaged with radial methods such as UTE result in mainly artefact-free images
… deformation maps that may provide information about the functional properties of the lung. …

Micro-computed tomography imaging of a rodent model of chronic obstructive pulmonary disease (copd)

NL Ford, I Lee, A Tam, DD Sin - … , and Functional Imaging, 2020 - spiedigitallibrary.org
lung structure and lung function in mice following chronic exposure to tobacco cigarettes using
respiratory-gated micro-CT imaging. … image-based analysis of in vivo micro-CT images to …

Investigating lung responses with functional hyperpolarized xenon‐129 MRI in an ex vivo rat model of asthma

DML Lilburn, AL Tatler, JS Six… - Magnetic …, 2016 - Wiley Online Library
… Later developments using more sophisticated models studied dynamic ventilatory changes
in healthy rodent lungs 34, 42. There are several similarities of the experimental setup …

[PDF][PDF] Understanding the Structural and Functional Correlates of Acute Lung Inflammation in Two Murine Models

M Kaur - 2022 - harvest.usask.ca
… in rodent lungs as compared to the structure of the human lungs, because rodent lung
be quantitatively visualized with various functional imaging methods such as single photon …

Novel imaging-derived morphological and functional biomarkers of lung disease in mouse models

K Dekoster - 2022 - lirias.kuleuven.be
… latter one is not without risk in small rodent animals 117-119. A … lung volume. As this would
enable non-invasive evaluation of lung function, we extracted and validated lung function

Magnetic resonance imaging provides sensitive in vivo assessment of experimental ventilator-induced lung injury

DO Kuethe, PT Filipczak, JM Hix… - … of Physiology-Lung …, 2016 - journals.physiology.org
image is a function of location, so we calculate the noise in the lung region by subtracting two
consecutive images … Although our study addresses MR lung imaging only in rodent models …

First in vivo magnetic particle imaging of lung perfusion in rats

XY Zhou, KE Jeffris, YY Elaine, B Zheng… - Physics in Medicine …, 2017 - iopscience.iop.org
… to the lungs. Here, we report a method for preparing a novel MPI lung perfusion imaging agent,
… demonstrate its efficacy and biodistribution for in vivo MPI lung perfusion imaging in rats. …

Three-dimensional quantitative co-mapping of pulmonary morphology and nanoparticle distribution with cellular resolution in nondissected murine lungs

L Yang, A Feuchtinger, W Möller, Y Ding… - ACS …, 2018 - ACS Publications
… have made the lung a particularly elusive inner organ for LSFM even for small rodent models
(… animal models ex vivo LSFM imaging is much more conducive to bioactivity and functional

[HTML][HTML] Assessing the relationship between lung density and function with oxygen-enhanced magnetic resonance imaging in a mouse model of emphysema

M Zurek, L Sladen, E Johansson, M Olsson… - PLoS …, 2016 - journals.plos.org
rodent OE-MRI imaging … of lung density and function in a mouse model of PPE-induced
emphysema. An ultrashort echo-time imaging sequence that enables the depiction of lung