[HTML][HTML] PET imaging to assess the impact of P-glycoprotein on pulmonary drug delivery in rats

I Hernández-Lozano, S Mairinger, T Filip… - Journal of Controlled …, 2022 - Elsevier
functional impact of P-gp on the pulmonary delivery of inhaled drugs in rats. By using positron
emission tomography (PET) imaging, … (eg isolated perfused rodent lungs) approaches or …

[HTML][HTML] … of Lung Function: from Micro to Macro: Magnetic resonance imaging provides sensitive in vivo assessment of experimental ventilator-induced lung injury

DO Kuethe, PT Filipczak, JM Hix… - … of Physiology-Lung …, 2016 - ncbi.nlm.nih.gov
image is a function of location, so we calculate the noise in the lung region by subtracting two
consecutive images … Although our study addresses MR lung imaging only in rodent models …

Imaging mass spectrometry to visualise increased acetylcholine in lungs of asthma model mice

T Matsuda, Y Suzuki, T Fujisawa, Y Suga… - Analytical and …, 2020 - Springer
… The rodent lung is composed of four right lobes and one left lobe. In this study, we used the
… the HDM group had asthma-like functional disturbances in their lungs. Moreover, an Alum …

In-vivo lung fibrosis staging in a bleomycin-mouse model: a new micro-CT guided densitometric approach

L Mecozzi, M Mambrini, F Ruscitti, E Ferrini… - Scientific reports, 2020 - nature.com
… free access to standard rodent chow and softened tap … lung capacity (TLC) or at functional
residual capacity (FRC) 9,40 whereas, to address free breathing variabilities, mice imaged by …

Pre‐and postnatal lung development: an updated species comparison

G Lewin, ME Hurtt - Birth defects research, 2017 - Wiley Online Library
… updated review of the ontogeny of lung structure and function. The main focus here will be
on the … In some species with altricial lung morphology, such as rodents, there is evidence of a …

… micro-CT provides biomarkers of lung disease that can be used to assess the effect of therapy in preclinical mouse models, and reveal compensatory changes in lung …

G Vande Velde, J Poelmans… - Disease models & …, 2016 - journals.biologists.com
… After the last time point, we performed pulmonary function tests and isolated the lungs for
histology… growth versus lung disease progression in rodent models remains largely unexplored. …

Chemokine receptor 2–targeted molecular imaging in pulmonary fibrosis. A clinical trial

SL Brody, SP Gunsten, HP Luehmann… - American journal of …, 2021 - atsjournals.org
… mixed with rodent chow at 0.5% by weight (24). Mouse … in lungs removed from patients with
pulmonary fibrosis at lung … and three women) with normal lung function (Table E3, human …

Functional vascularized lung grafts for lung bioengineering

NV Dorrello, BA Guenthart, JD O'Neill, J Kim… - Science …, 2017 - science.org
… method by using a rodent lung model. Following lung cannulation, lungs were ventilated and
… We demonstrate a transformative approach to obtaining functional vascularized lung grafts. …

Longitudinal micro-CT provides biomarkers of lung disease and therapy in preclinical models, thereby revealing compensatory changes in lung volume

GV Velde, J Poelmans, E De Langhe… - Dis. Model …, 2016 - journals.biologists.com
… normal growth versus lung disease progression in rodent models remains largely …
Preclinical anatomical, molecular, and functional imaging of the lung with multiple modalities…

Single-cell connectomic analysis of adult mammalian lungs

MSB Raredon, TS Adams, Y Suhail, JC Schupp… - Science …, 2019 - science.org
… As maintaining barrier function is arguably the foremost design criterion in lung tissue … min
for the rodent tissues and 40 min for the large mammals. At this point, the lungs were pushed …