Preclinical applications of multi-platform imaging in animal models of cancer

NJ Serkova, K Glunde, CR Haney, M Farhoud… - Cancer research, 2021 - AACR
… B, Physiology-based images in rodent cancer models: (7) high … enhanced microCT of lung
vasculature and small lung tumor using … An anatomic and functional imaging probe for a novel …

Stereological monitoring of mouse lung alveolarization from the early postnatal period to adulthood

A Pozarska, JA Rodríguez-Castillo… - … of Physiology-Lung …, 2017 - journals.physiology.org
… in the lung being reported in humans, as well as in rodent models. In response to this,
concomitant with advances in our knowledge of lung … how structural change impact lung function. …

Correlating local volumetric tissue strains with global lung mechanics measurements

H Arora, RL Mitchell, R Johnston, M Manolesos… - Materials, 2021 - mdpi.com
… that influence mechanics and function. This study establishes an … Rodent lungs were
mechanically ventilated and imaged at … functional residual capacity and up to 50% of their total …

Vascular casting of adult and early postnatal mouse lungs for micro-CT imaging

RH Knutsen, LM Gober, JR Sukinik… - JoVE (Journal of …, 2020 - jove.com
… Executed properly, this method yields striking images of pulmonary arterial networks, allowing
for comparison and experimentation in rodent models. Several critical steps along the way …

Hemodynamic characterization of rodent models of pulmonary arterial hypertension

Z Ma, L Mao, S Rajagopal - JoVE (Journal of Visualized Experiments), 2016 - jove.com
… of these rodent models of PH is required, and involves assessments of RV function (typically …
cardiac catheterization) and histopathology of the heart and lungs (from tissue harvesting). …

The role of hyperpolarized 129xenon in MR imaging of pulmonary function

L Ebner, J Kammerman, B Driehuys… - European journal of …, 2017 - Elsevier
… In the last two decades, functional imaging of the lungs using hyperpolarized noble gases
… These properties were first demonstrated in preclinical rodents and canine models, yielding …

Pulmonary mechanics and structural lung development after neonatal hyperoxia in mice

AM Dylag, J Haak, M Yee, MA O'Reilly - Pediatric research, 2020 - nature.com
lung disease and abnormal pulmonary function. This study used mild (40%), moderate (60%),
and severe (80%) oxygen to determine how hyperoxia-induced changes in lungrodents

On The Functional Dynamics of Alveolar and Ductal Growth in The Adolescent Lung

R Moats, D Koos, W Shi, Y Tang, H Pollack, D Tipre… - 2021 - researchsquare.com
imaging coupled with qualitative and quantitative analysis, we suggest the bulk of alveolarization
during adolescent lung … the growth of lung and it’s structural and functional parameters, …

Tiny golden angle ultrashort echo‐time lung imaging in mice

A Balasch, P Metze, H Li, W Rottbauer… - NMR in …, 2021 - Wiley Online Library
… Further, this study only proves the principal use of the tyGA technique for lung function imaging
… strong evidence about the potential role of 2D tyGA for functional lung imaging in rodents. …

Imaging phenotype of occupational endotoxin-related lung function decline

PS Lai, J Hang, F Zhang, J Sun… - Environmental …, 2016 - ehp.niehs.nih.gov
… identify imaging biomarkers associated with lung function decline. … lung function data,
cross-sectional CT measures of lung mass may serve as a biomarker for accelerated lung function