Update on the features and measurements of experimental acute lung injury in animals: an official American Thoracic Society workshop report

HS Kulkarni, JS Lee, JA Bastarache… - American journal of …, 2022 - atsjournals.org
… , accurate measure of lung mechanics in small rodents. Third, a … First, impaired lung function,
specifically reduced respiratory … who suggested lung function measurements recommended …

SARS-CoV-2 infection in the lungs of human ACE2 transgenic mice causes severe inflammation, immune cell infiltration, and compromised respiratory function

ES Winkler, AL Bailey, NM Kafai, S Nair, BT McCune… - BioRxiv, 2020 - biorxiv.org
lung tissues with additional spread to other organs. Remarkably, a decline in pulmonary
function, … response marked by infiltration into the lung of monocytes, neutrophils, and activated T …

Quantification of pulmonary fibrosis in a bleomycin mouse model using automated histological image analysis

JC Gilhodes, Y Julé, S Kreuz, B Stierstorfer, D Stiller… - PloS one, 2017 - journals.plos.org
… In the absence of a well-established gold standard to quantify fibrotic changes in rodents with
… (2014) Preclinical anatomical, molecular, and functional imaging of the lung with multiple …

Maintenance of deep lung architecture and automated airway segmentation for 3D mass spectrometry imaging

AJ Scott, CE Chandler, SR Ellis, RMA Heeren… - Scientific Reports, 2019 - nature.com
… the tissue architecture and functional space that normally exists as … involving lung tissue. To
achieve high quality histology from … In this work, we present a method for rodent lung inflation …

Novel method for functional brain imaging in awake minimally restrained rats

PC Chang, D Procissi, Q Bao… - Journal of …, 2016 - journals.physiology.org
Functional magnetic resonance imaging (fMRI) in rodents holds great promise for … of
functional images into a standard space, many images supplementary to functional images were …

[PDF][PDF] Respiratory-gated KES imaging of a rat model of acute lung injury at the Canadian Light Source

P Deman, S Tan, G Belev, N Samadi… - Journal of …, 2017 - journals.iucr.org
… phase and is feasible for imaging disease models with compromised lung function. … of
imaging rodent respiratory structures and pulmonary vasculature together in rodent models of …

Imaging techniques to study drug transporter function in vivo

N Tournier, B Stieger, O Langer - Pharmacology & therapeutics, 2018 - Elsevier
functional imaging technique which only gives limited anatomical information. For the
delineation of organ substructures on PET images… where not observed in rodents, or vice versa. …

… positron emission tomography depicts heterogeneous proliferation pathology in idiopathic pulmonary arterial hypertension patient lung: a potential biomarker for …

A Ashek, OA Spruijt, HJ Harms… - … Imaging, 2018 - Am Heart Assoc
… chose to discard the RV input function to avoid potential issues of … imaging in patients with
IPAH and rodent PAH models to report on pulmonary vascular pathology. We found that lung

Human Organotypic Lung Tumor Models: Suitable For Preclinical 18F-FDG PET-Imaging

D Fecher, E Hofmann, A Buck, R Bundschuh, S Nietzer… - PloS one, 2016 - journals.plos.org
… [27] and in vitro generated transplantable rodent lung tissue from a … a 3D organotypic lung
tumor model in which lung tumor … to set up functional imaging with FDG-PET for the lung tumor …

In vivo imaging of mitochondrial membrane potential in non-small-cell lung cancer

M Momcilovic, A Jones, ST Bailey, CM Waldmann, R Li… - Nature, 2019 - nature.com
lung cancer, and find distinct functional mitochondrial heterogeneity within subtypes of lung
… F-BnTP has been studied in rodent and canine myocardium to detect myocardial infarction 4…