Molecular investigation into spinal cord injury regeneration barriers and therapeutic strategies

H Baumann - 2020 - search.proquest.com
… therapy, improve functional outcomes, but do not cure spinal cord injury induced deficits. …
elastic material properties of a chronic rat hemi-section SCI model using AFM, and to correlate …

Stem Cell-and Biomaterial-Based Neural Repair for Enhancing Spinal Axonal Regeneration

L Yao, P Kaphle, L Yao, J Kehler - Glial Cell Engineering in Neural …, 2018 - Springer
… into a spinal cord lesion of a rat model. The graft of the cells improved spinal motor recovery
… designed with enhanced response to injury-induced signals such as the chemokine stromal …

Modern Approaches to Tissue Engineering of the Spinal Cord: Analytical Review

IN Bolshakov, SL Kiselev… - … Formerly: Recent Patents …, 2017 - ingentaconnect.com
… ) in a rat model of contusion SCI revealed the post-transplant … animals shows only insignificant
functional improvement. The … rat spinal cord contusion injury model in comparison with the …

Human Deep Cortical Neurons Promote Regeneration and Recovery After Cervical Spinal Cord Injury

VM Doulames, J Weimann, GW Plant - bioRxiv, 2021 - biorxiv.org
improving function. Herein we report robust regeneration of severed neural circuitry in a rat
… Therefore, we sought to intraspinally transplant a cellular population that could support and …

[HTML][HTML] Potential role of hippocampal neurogenesis in spinal cord injury induced post-trauma depression

Y Ma, Y Qiao, X Gao - Neural Regeneration Research, 2024 - journals.lww.com
… , neuropathic pain, spasticity, and neurogenic bladder and … To further augment our
understanding, we reviewed currently … , some treatments also improve locomotor function that will …

Stem Cell Therapies for Cervical Spinal Cord Injury

VM Doulames, LM Marquardt, B Jayaram… - … Spinal Cord Injury, 2016 - books.google.com
… BMSCs transplanted into the rat spinal cord after a contusion … able to reverse injury induced
inflammation by reducing pro-… often dependent on the extracellular matrix and growth factor …

Investigations of potential mechanisms underlying spinal cord injury-induced polyuria.

JH Gumbel - 2021 - ir.library.louisville.edu
… for potential targeted therapies to improve quality of life. The objective … in urine production
based on their physiologic function. … We have opted to utilize only adult male rats for the current …

Anti-chondroitin sulfate proteoglycan strategies in spinal cord injury: temporal and spatial considerations explain the balance between neuroplasticity and …

T Hryciw, NM Geremia, MA Walker, X Xu… - Journal of …, 2018 - liebertpub.com
… The hemisection injury induced elevated CSPG levels within 1–2 mm … of the graft, indicating
that improvements were indeed … and developmentally distinct regions of rat spinal cord. Cell …

Dynamics of biomarkers across the stages of traumatic spinal cord injury-implications for neural plasticity and repair

T Begenisic, C Pavese, B Aiachini… - Restorative …, 2021 - content.iospress.com
… both adaptive (promoting functional improvement) and maladaptive… Injury-induced plasticity
leads to NGF-dependent … by cryogenic lesion in the spinal cord of adult rats, it was shown …

[HTML][HTML] Role of descending serotonergic fibers in the development of pathophysiology after spinal cord injury (SCI): Contribution to chronic pain, spasticity, and …

GNK Fauss, KE Hudson, JW Grau - Biology, 2022 - mdpi.com
… cells were grafted into the lesion site of T4 transected rats [299]. Functional innervation of …
dissociation of the time-course of injury-induced changes in KCC2 and the development of …