… However, G-CSF (40 µg/kg) significantly reduced these three indicators (Fig. 1D,E). When …
CXCR4 on bone marrow stem cells induced by G-CSF. Petit et al. found that G-CSF mobilized …

… cognitive decline [22], the understanding of the fate of G-CSF-… the migration and homing of
stem cells in the developmental … of G-CSF-induced HSC mobilization combined with SDF-1 …

… Disruption of the CXCR4/SDF-1 chemotactic interaction during G-CSF-… SDF-1 depletion in
the bone marrow, following G-CSF application, causes release of blood progenitor stem cells …

… , and its receptor CXCR4. HSC mobilization in response to cytokines such as G-CSF or to …
osteopetrosis again found no effect on G-CSF-induced HSPC mobilization [46]. These later …

… stromal cell-derived factor-1 (SDF-1/CXCL12) in bone marrow … the changes in the SDF-1/CXCR4
axis induced by G-CSF [48•… inactivate SDF-1, and as described, reduced marrow SDF-1 …

… SDF-1/CXCR4 axis in the regulation of MSC migration, we speculated that the combination
of G-CSF and/or AMD3100 (CXCR4 … marrow SDF-1 and up-regulating CXCR4. Nat Immunol …

… for interaction between bone marrow-derived stromal stem cells (… The interaction of SDF-1
with CXCR4 causes the cells to … The level of SDF-1 in bone marrow is decreased by G-CSF (…

… /CXCR4 interactions in G-CSF-mediated mobilization is … of G-CSF induced mobilization in
CXCR4 −/− bone marrow chimeric … bone marrow are dramatically reduced during mobilization …

… and SDF-1/CXCR4 have critical roles in homing hematopoietic … responses of HSPC towards
SDF-1 by up regulating MT1-MMP … G-CSF downregulates the expression of CXCR4 on cells …

… phenotypic HSCs in bone marrow (BM), induction of HSC … 12, CXCR4: CXC Motif Chemokine
Receptor 4, G-CSF: … cytokines G-CSF and TNFα produced by bone marrow stromal cells …