Enduring memory impairments provoked by developmental febrile seizures are mediated by functional and structural effects of neuronal restrictive silencing factor

KP Patterson, JM Barry, MM Curran… - Journal of …, 2017 - Soc Neuroscience
… Blocking NRSF transiently after eFSE prevented granule cell … common developmental
seizures that provoke epilepsy in a … by KA-induced seizures like events, we applied, following the …

Inhibitory or excitatory? Optogenetic interrogation of the functional roles of GABAergic interneurons in epileptogenesis

H Ye, S Kaszuba - Journal of Biomedical Science, 2017 - Springer
… accelerated propagation in febrile seizures, and reduced threshold in flurothyl-induced
granule cell ectopia in the dentate gyrus after febrile seizures, and the development of epilepsy

Adult born dentate granule cell mediated upregulation of feedback inhibition in a mouse model of traumatic brain injury

YJ Kang, SH Lee, JA Boychuk, CR Butler… - Journal of …, 2022 - Soc Neuroscience
… to hyperexcitability in post-traumatic epilepsy (PTE). However, … with GABAergic interneurons
and mature DGCs after TBI. … when brain injury was induced; termed “adult born pre-CCI”), 7-…

Under New Management: Transplanted GABAergic Progenitors Control Adult Neurogenesis

GF Buchanan - Epilepsy currents, 2023 - journals.sagepub.com
… These ectopic cells mature into granule cells in the hilus that … mice with Pilocarpine induced
TLE, hilar transplants of GABA … some inciting event (eg, febrile seizure, in utero insult, injury, …

The dentate gyrus and temporal lobe epilepsy: an “exciting” era

HE Scharfman - Epilepsy Currents, 2019 - journals.sagepub.com
… is that methods to induce epilepsy in rodents became … with epilepsy expressed GABA as well
as glutamate, 45 and … When recordings were made of the hilar “ectopicgranule cells (EGCs…

Microglia after seizures and in epilepsy

T Hiragi, Y Ikegaya, R Koyama - Cells, 2018 - mdpi.com
… reduced the number of acute seizures in KA-induced epileptic mice [41]… , which implies that
CX3CL1 promotes the stability of GABA-… granule cells in the epileptic brain, especially ectopic

Suppressive Effects of Docosahexaenoic Acid Intake on Increased Seizure Susceptibility after Growth Due to Febrile Seizures in Infancy

S Kawano, K Itoh, Y Ishihara - Biological and Pharmaceutical Bulletin, 2023 - jstage.jst.go.jp
after febrile seizures to prevent post-growth epilepsy. The … acid-A receptors in neonatally
generated granule cells, and their … febrile seizures induce abnormal neuronal activity even after

Heat-shock induces granule cell dispersion and microgliosis in hippocampal slice cultures

J Weninger, M Meseke, S Rana… - Frontiers in Cell and …, 2021 - frontiersin.org
… lobe epilepsy (TLE) and a history of febrile seizures but was … Febrile seizures and ectopic
granule cell positioning were … granule cell migration was caused by excitatory GABAergic

Corruption of the dentate gyrus by “dominant” granule cells: Implications for dentate gyrus function in health and disease

HE Scharfman, CE Myers - Neurobiology of learning and memory, 2016 - Elsevier
… model of epilepsy, where febrile seizures in young animals are used to induce the epilepsy,
… The normal depolarizing influence of GABA in developing GCs, a very important signal for …

Bumetanide reduce the seizure susceptibility induced by pentylenetetrazol via inhibition of aberrant hippocampal neurogenesis in neonatal rats after hypoxia …

JJ Hu, XL Yang, WD Luo, S Han, J Yin, WH Liu… - Brain research …, 2017 - Elsevier
epilepsy (TLE) and corresponding animal models, ectopically located granule cells are found
in the dentate hilus (ectopic granule … In a complex febrile seizures rat model, bumetanide …