… in our understanding of GLUT4 expression and translocation… of Slc2a4 mRNA and GLUT4
protein, and GLUT4 translocation in … particular questions related to GLUT4 system and insulin …

… The level of GLUT4 in cell surface is determined by the regulation of GLUT4 endocytosis
and exocytosis. GLUT4 translocation to plasma membrane through …

… Consistent with this, gbSTX4tg increases plasma membrane GLUT4 density in mice …
exocytosis in other cell types 9 . Hence, it is not known whether STX4-mediated regulation of GLUT4 …

… by adjusting the endo- and exocytosis rates accordingly, suggesting that GLUT4 remains
within this cycling … These studies indicate, that VAMP2 plays a major role in GLUT4 exocytosis. …

… In addition to insulin primarily targeting GLUT4 exocytosis, studies on photolabel-tagged
GLUT4 have revealed that there are at least two phases to the insulin response. First, there is a …

… 6F) and suggests that the observed decrease in GLUT4 exocytosis in Sx4-knockout cells
occurs at a different intracellular trafficking step. This is discussed further below. …

… GLUT4 retrieval from the PM through coupling GLUT4 to CHC17. To evaluate an AnkB-dependent
interaction between GLUT4 … (PLAs) for GLUT4 and CHC17, GLUT4 and AnkB, and …

… These data demonstrate insulin-stimulated GLUT4 exocytosis is regulated by both
TBC1D4-RAB10-dependent and -independent mechanisms. Overexpressed RAB10 has been …

… Finally, sequential or compound exocytosis of insulin is repressed to prevent sugar crash …
scenarios which are behind insulin biogenesis, intracellular sorting and exocytosis events. …

… We report that insulin induces redistribution of GLUT4 to the PM by accelerating exocytosis,
which is consistent with previous studies of rodent muscle cells (Sylow et al., 2021), whereas …