Neferine promotes GLUT4 expression and fusion with the plasma membrane to induce glucose uptake in L6 cells

P Zhao, D Tian, G Song, Q Ming, J Liu… - Frontiers in …, 2019 - frontiersin.org
… GSVs transfer GLUT4 to the plasma membrane under the stimulation of insulin, thus … GLUT4
expression via the G protein-PLC-PKC and AMPK pathways, thus promoting GLUT4 fusion …

CFTR deficiency affects glucose homeostasis via regulating GLUT4 plasma membrane transportation

J Gu, W Zhang, L Wu, Y Gu - Frontiers in Cell and Developmental …, 2021 - frontiersin.org
… 4 (GLUT4) translocation to the cell membrane was abnormal in the CFTR knockout mice
muscle fibers, suggesting that defective intracellular GLUT4 … of CFTR in GLUT4 translocation …

Insights into Insulin Regulation of GLUT4 Trafficking at the TGN

A Brumfield - 2020 - search.proquest.com
GLUT4 translocation by 50% (46-48). These data demonstrate insulin-stimulated GLUT4
exocytosis … focuses on identifying the step in GLUT4 exocytosis that TBC1D4-RAB10 regulates, …

DHHC7 palmitoylates glucose transporter 4 (Glut4) and regulates Glut4 membrane translocation

K Du, S Murakami, Y Sun, CL Kilpatrick… - Journal of Biological …, 2017 - ASBMB
… of Glut4 at Cys-223. To gain further insights into the regulation of Glut4 palmitoylation, we set
… Here we report that among 23 mammalian DHHC proteins, DHHC7 is the major Glut4 PAT, …

Regulation of GLUT4 translocation in adipocytes: the role of SNARE proteins and caveolae

H Taylor - 2023 - stax.strath.ac.uk
Background: Following a meal, insulin stimulates the translocation of the glucose transporter
GLUT4 to the plasma membrane (PM) of fat and muscle cells, resulting in increased …

[PDF][PDF] THE PHOSPHATIDYLETHANOLAMINE DERIVATIVE diDCP-LA-PE STIMULATES VESIVULAR GLUT4 EXOCYTOSIS BY INTERACTING WITH NSF

T Nishizaki - academia.edu
… by the vesicular exocytosis inhibitorbotulinum toxin-A. diDCP-LA-PE-induced GLUT4 translocation
is … These results indicate that diDCP-LA-PE stimulates vesicular GLUT4 exocytosis by …

Metabolic control of type 2 diabetes by targeting the GLUT4 glucose transporter: intervention approaches

F Alam, A Islam, I Khalil… - Current pharmaceutical …, 2016 - ingentaconnect.com
… , and increased signaling, as well as changes in GLUT4 protein exocytosis and endocytosis
[117]. The effects of exercise on GLUT4 and glucose uptake have been established in many …

Rab28 is a TBC1D1/TBC1D4 substrate involved in GLUT4 trafficking

Z Zhou, F Menzel, T Benninghoff, A Chadt, C Du… - FEBS …, 2017 - Wiley Online Library
… been described to be associated to GLUT4-containing vesicles [33, 34]. Rab3B, Rab8, and
Rab10 were suggested play roles in the exocytosis of GLUT4 vesicles, whereas Rab14 may …

GLUT4 translocation in single muscle cells in culture: epitope detection by immunofluorescence

JR Jaldin-Fincati, PJ Bilan, A Klip - Glucose Transport: Methods and …, 2018 - Springer
… in surface GLUT4 [3]. In contrast, during conditions of energy demand, GLUT4 endocytosis
… exercise may increase GLUT4-containing vesicle exocytosis and delay GLUT4 endocytosis. …

Complexin-2 redistributes to the membrane of muscle cells in response to insulin and contributes to GLUT4 translocation

MA Pavarotti, V Tokarz, S Frendo-Cumbo… - Biochemical …, 2021 - portlandpress.com
GLUT4 translocation largely depends on the acceleration of the exocytic rate of GLUT4-containing
vesicles (hereon GLUT4 … to insert the GLUT4 transmembrane protein [1–4]. Defective …