GM3 Induces Terminal Differentiation of Leukemic Cells
CH Kim, CH Kim - GM3 Signaling, 2020 - Springer
… -induced differentiation of the human leukemic monocytic … lineage cells normally express
a lot of GM3 ganglioside. … during megakaryocytoid differentiation of PMA-induced K562 cells. …
a lot of GM3 ganglioside. … during megakaryocytoid differentiation of PMA-induced K562 cells. …
Membrane Ganglioside-Specific Neuraminidase 3 (NEU3) Regulates GM3 Signaling
CH Kim, CH Kim - GM3 Signaling, 2020 - Springer
… ) synthase, blocks the megakaryocytic differentiation in K562 cells… GM3 is an inducing
modulator of megakaryocytoid cell differentiation, as confirmed by human erythroleukemic K562 …
modulator of megakaryocytoid cell differentiation, as confirmed by human erythroleukemic K562 …
3′-sialyllactose targets cell surface protein, SIGLEC-3, and induces megakaryocyte differentiation and apoptosis by lipid raft-dependent endocytosis
SH Ha, CH Kwak, JY Park, F Abekura, YC Lee… - Glycoconjugate …, 2020 - Springer
… to the ganglioside GM3 [9]. In the previous study [10, 11], it was shown that GM3 regulates
… To define the type of differentiated cell linage induced by 3SL, K562 cells were treated with …
… To define the type of differentiated cell linage induced by 3SL, K562 cells were treated with …
[HTML][HTML] Induction of GD3/α1-adrenergic receptor/transglutaminase 2-mediated erythroid differentiation in chronic myelogenous leukemic K562 cells
SH Ha, SK Kang, H Choi, CH Kwak, F Abekura… - Oncotarget, 2017 - ncbi.nlm.nih.gov
… 4A), the expression of the ganglioside GD3 was clearly increased in K562 cells treated
with 10 μM epinephrine. However, the levels of GM3 and GD1a were diminished, as measured …
with 10 μM epinephrine. However, the levels of GM3 and GD1a were diminished, as measured …
[HTML][HTML] Novel function of FAXDC2 in megakaryopoiesis
Q Jin, Y Ren, M Wang, PK Suraneni, D Li… - Blood cancer …, 2016 - nature.com
… (TPA)-induced megakaryocytic differentiation of K562 cells has … ), discovered in human
leukemia has been demonstrated to … through the increase of ganglioside GM3 resulting in the …
leukemia has been demonstrated to … through the increase of ganglioside GM3 resulting in the …
[图书][B] GM3 Signaling
CH Kim - 2020 - Springer
… Ganglioside GM3 has advantages as a potential therapeutic agent. As … -like cell differentiation
can induce monocytic differentiation of human myeloid and monocytoid leukemic cell lines …
can induce monocytic differentiation of human myeloid and monocytoid leukemic cell lines …
[HTML][HTML] Inhibition of glycosphingolipid biosynthesis reverts multidrug resistance by differentially modulating ABC transporters in chronic myeloid leukemias
… alter these processes on human leukemias, the expression … a mix of GM1, GM2, and GM3
is indicated on the left of the … than on K562 suggest that this sphingolipid induces collateral …
is indicated on the left of the … than on K562 suggest that this sphingolipid induces collateral …
[HTML][HTML] Serum GM3 (d18: 1-16: 0) and GM3 (d18: 1-24: 1) levels may be associated with lymphoma: An exploratory study with haematological diseases
M Nishikawa, M Kurano, T Nitta, H Kanoh, J Inokuchi… - Scientific Reports, 2019 - nature.com
… of GM3 is about 48% of total ganglioside content 11 . … the induction of differentiation in
several blood cell lines 5 and to determine the direction of differentiation in pluripotent K562 cells …
several blood cell lines 5 and to determine the direction of differentiation in pluripotent K562 cells …
[HTML][HTML] The role of sialyltransferases in gynecological malignant tumors
Y Zhang, R Wang, Y Feng, F Ma - Life Sciences, 2020 - Elsevier
… known as GM3 synthase, in leukemia cell lines HL-60 and k562, … may have a crucial rule in
inducing the expression of ST3Gal5 [24,… of gangliosides and STs in neuroepithelial cells were …
inducing the expression of ST3Gal5 [24,… of gangliosides and STs in neuroepithelial cells were …
Regulatory mechanism for the human glioblastoma cell-specific expression of the human GD1c/GT1a/GQ1b synthase (hST8Sia V) gene
… induces the increase in the ganglioside GQ1b production in human glioblastoma U87MG cells
was … biosynthesis, such as human GM3 synthase (hST3Gal V) and human GD3 synthase (…
was … biosynthesis, such as human GM3 synthase (hST3Gal V) and human GD3 synthase (…