Biological functions of connexin43 beyond intercellular communication

T Martins-Marques, T Ribeiro-Rodrigues… - … in cell biology, 2019 - cell.com
… with direct cellcell communication through gap junctions (GJs). However, recent groundbreaking
studies have challenged this dogma, implicating Cx43 in other biological processes, …

Gap junctional intercellular communication as a method to detect and predict carcinogenicity

V Krutovskikh, H Yamasaki - Carcinogenicity, 2021 - taylorfrancis.com
… However, advances in gap junction molecular biology revealed an essential difference
between hepatocytes in vivo and their corresponding established cell lines in terms of the pattern …

Gap junctions and cancer: communicating for 50 years

T Aasen, M Mesnil, CC Naus, PD Lampe… - Nature Reviews …, 2016 - nature.com
… to be effective inhibitors of gap junctional intercellular communication (GJIC) and metabolic
… linked to cancer biology, which are reviewed extensively elsewhere 59,60,61,62,63,66 . …

[HTML][HTML] Gap junction-dependent and-independent functions of Connexin43 in biology

Y Zhu - Biology, 2022 - mdpi.com
… family genes; connexin genes took over the gap junction function for the first time in the … for
intercellular communication [3]. After the connexin proteins took over the gap junction function…

Connexin and gap junctions: perspectives from biology to nanotechnology based therapeutics

S Jindal, S Chockalingam, SS Ghosh… - Translational …, 2021 - Elsevier
… The concept of gap junctions and their role in intercellular communication has been known
… the fundamental biology of connexins in mediating gap junction intercellular communication (…

[HTML][HTML] Cell systems bioelectricity: how different intercellular gap junctions could regionalize a multicellular aggregate

A Riol, J Cervera, M Levin, S Mafe - Cancers, 2021 - mdpi.com
… obtain with only one type of connexin gap junction for biologically plausible single-cell and
… been further reflected in distinct intercellular communication and reduced resting membrane …

[HTML][HTML] Cancer connectors: connexins, gap junctions, and communication

M Sinyuk, EE Mulkearns-Hubert, O Reizes… - Frontiers in …, 2018 - frontiersin.org
… direct gap junction intercellular communication (GJIC) between cells, form hemichannels to
allow cell communication … Consequently, connexin biology can be broadly classified by three …

Inhibition of gap junction intercellular communication is involved in silica nanoparticles-induced H9c2 cardiomyocytes apoptosis via the mitochondrial pathway

Z Du, G Cui, J Zhang, X Liu, Z Zhang, Q Jia… - International journal …, 2017 - Taylor & Francis
Intercellular communication through gap junctions plays a critical role in a variety of
cellular and biological processes, including regulation of cell growth and differentiation, …

[HTML][HTML] Gap junctional intercellular communication dysfunction mediates the cognitive impairment induced by cerebral ischemia-reperfusion injury: PI3K/Akt pathway …

S Zhou, Z Fang, G Wang, S Wu - American Journal of Translational …, 2017 - ncbi.nlm.nih.gov
… role of gap junctional intercellular communication in cognitive … the role of gap junctional
communication dysfunction in the rat … with a Bradford reagent (Bio-Rad Co., Hercules, CA, USA). …

[HTML][HTML] Possible mechanisms of mercury toxicity and cancer promotion: involvement of gap junction intercellular communications and inflammatory cytokines

R Zefferino, C Piccoli, N Ricciardi, R Scrima… - … medicine and cellular …, 2017 - hindawi.com
gap junction-mediated intercellular communication are, however, yet to be fully elucidated.
Deregulation of gap junctional intercellular communication … ,” Free Radical Biology & Medicine…