Safety of gefitinib in non-small cell lung cancer treatment

EHC Hsiue, JH Lee, CC Lin… - Expert opinion on drug …, 2016 - Taylor & Francis
… continued the approval of gefitinib because OS benefit was observed in the preplanned
subset analysis in the Asian patients in this study [Citation10]. In 2009, gefitinib was approved by …

[HTML][HTML] Comparing gefitinib and traditional chemotherapy for better survival in patients with non-small cell lung cancer: A systematic review

S Kanagalingam, ZU Haq, NV Srinivasan, AI Khan… - Cureus, 2023 - ncbi.nlm.nih.gov
… chemotherapy had EGFR mutation but could not get EGFR-TKIs because of the cost associated
with the drug in China, as most patients had to pay out of pocket, in turn limiting its use [3]…

… survival in a randomized study comparing dacomitinib with gefitinib as first-line treatment in patients with advanced non-small-cell lung cancer and EGFR-activating …

TS Mok, Y Cheng, X Zhou, KH Lee, K Nakagawa… - Drugs, 2021 - Springer
… , versus gefitinib in treatment-naïve patients with advancedanalysis showed that dacomitinib
was superior to gefitinib … independent radiologic central (BIRC) review (hazard ratio [HR…

Study of gefitinib and pemetrexed as first-line treatment in patients with advanced non-small cell lung cancer harboring EGFR mutation

C An, J Zhang, H Chu, C Gu, F Xiao, F Zhu… - Pathology & Oncology …, 2016 - Springer
… Patients with advanced non-… into gefitinib + placebo group and gefitinib + pemetrexed
group. Pemetrexed or placebo was administered on day 1 at a dose of 500 mg/m 2 , and gefitinib

Gefitinib provides similar effectiveness and improved safety than erlotinib for east Asian populations with advanced nonsmall cell lung cancer: a meta-analysis

W Zhang, Y Wei, D Yu, J Xu, J Peng - BMC cancer, 2018 - Springer
gefitinib and erlotinib have both been proven effective for treating advanced nonsmall cell
lung cancer (… We conducted this meta-analysis to compare their efficacy and safety in treating …

Chemotherapy and intercalated gefitinib or erlotinib in the treatment of advanced non-small-cell lung cancer

A Rossi, A La Salvia, M Di Maio - … Review of Respiratory Medicine, 2017 - Taylor & Francis
… of advanced non-small-cell lung cancer (NSCLC). This review will summarize and discuss
the clinical results available to date from prospective studies investigating this approach. …

Treatment of advanced non-small cell lung cancer in the elderly

PC Sacco, P Maione, G Palazzolo… - Expert Review of …, 2018 - Taylor & Francis
… of gefitinib as first-line treatment, two retrospective analysis … the activity and feasible of gefitinib
treatment in patients aged … weeks after the start of gefitinib treatment. Regardless to toxicity…

EGFR tyrosine kinase inhibitor efficacy in older adult patients with advanced EGFR-mutated non-small-cell lung cancer: a meta-analysis and systematic review

CH Chen, DW Chou, KM Chung, HY Chang - Medicina, 2022 - mdpi.com
… 7 trial, there was no significant PFS and OS benefit when they were comparing afatinib with
gefitinib in older adult participants [12,13]. In the ARCHER 1050 trial, there was significant …

Comparison of gefitinib plus chemotherapy versus gefitinib alone for advanced non-small-cell lung cancer: A meta analysis

M Yi, T He, K Wang, Y Wei - Clinics, 2023 - SciELO Brasil
… a meta-analysis comparing the efficacy and safety of gefitinib in combination with chemotherapy
versus gefitinib alone in patients with advanced Non-Small Cell Lung Cancer (NSCLC). …

Dacomitinib versus gefitinib as first-line treatment for patients with EGFR-mutation-positive non-small-cell lung cancer (ARCHER 1050): a randomised, open-label …

YL Wu, Y Cheng, X Zhou, KH Lee, K Nakagawa… - The Lancet …, 2017 - thelancet.com
… growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib.
… vs gefitinib in advanced non-small cell lung cancer with EGFR mutations. Br J Cancer. 2017; …