[HTML][HTML] Gene therapy: advances, challenges and perspectives
GAR Gonçalves, RMA Paiva - Einstein (Sao Paulo), 2017 - SciELO Brasil
… Next, another Chinese group also reported the conduction of the same process done with …
any new technology, need more clarifying preclinical studies. In the future, there is the promise …
any new technology, need more clarifying preclinical studies. In the future, there is the promise …
Gene therapy comes of age
… discoveries leading to the development of successful gene … editing trials are expected to
open over the next decade. … clinical promise, and we will limit our discussions to these vectors. …
open over the next decade. … clinical promise, and we will limit our discussions to these vectors. …
Clinical development of gene therapy: results and lessons from recent successes
SRP Kumar, DM Markusic, M Biswas, KA High… - Molecular therapy …, 2016 - cell.com
… Therapeutic gene transfer holds the promise of providing … Advances in the development of
gene therapy vector systems, … in most patients, who were subsequently able to resolve pre-…
gene therapy vector systems, … in most patients, who were subsequently able to resolve pre-…
[HTML][HTML] The once and future gene therapy
K Bulaklak, CA Gersbach - Nature communications, 2020 - nature.com
… of therapies and laid the foundation for next-generation technologies. This comment summarizes
recent advances … Despite the promise of this approach, it does not address correction of …
recent advances … Despite the promise of this approach, it does not address correction of …
Gene therapy leaves a vicious cycle
R Goswami, G Subramanian, L Silayeva… - Frontiers in …, 2019 - frontiersin.org
… used in gene therapy, advances, challenges, and perspectives. … the next 10 years, both
clinical trials and pharmaceutical industry are anticipated to benefit immensely from gene therapy…
clinical trials and pharmaceutical industry are anticipated to benefit immensely from gene therapy…
Gene therapy for neurological disorders: progress and prospects
… Here, we discuss key considerations and challenges in the … advances have resulted in a
resurgence of interest in gene … substantial promise for achieving improved biological profiles for …
resurgence of interest in gene … substantial promise for achieving improved biological profiles for …
The promise and challenge of therapeutic genome editing
JA Doudna - Nature, 2020 - nature.com
… breakthroughs in agriculture and synthetic biology 6,7,8,9 . Building on past gene therapy
… The next section describes current genome-editing technologies that offer the potential of …
… The next section describes current genome-editing technologies that offer the potential of …
Nanoparticles for cancer gene therapy: Recent advances, challenges, and strategies
… Gene therapy holds unique promise in meeting these goals by offering a means of specific
… (5-FU) that is subsequently converted by endogenous enzymes into potent pyrimidine …
… (5-FU) that is subsequently converted by endogenous enzymes into potent pyrimidine …
Between hope and reality: treatment of genetic diseases through nucleic acid-based drugs
… After decades of promises, tempered by great deal of failures… 25 years after the first gene
therapy attempt to treat children … the MHRA represents a major breakthrough in the field. On …
therapy attempt to treat children … the MHRA represents a major breakthrough in the field. On …
Non-viral vectors in gene therapy: recent development, challenges, and prospects
H Zu, D Gao - The AAPS journal, 2021 - Springer
… Gene therapy has been experiencing a breakthrough in … The model has provided a new
tool to study the subsequent … cancer cells, which shows promise for targeted gene therapy. …
tool to study the subsequent … cancer cells, which shows promise for targeted gene therapy. …