Cell and gene therapy for kidney disease

JL Peek, MH Wilson - Nature Reviews Nephrology, 2023 - nature.com
… Current interventions for kidney disease include dialysis and renal transplantation, which
have limited efficacy or availability and are often associated with complications such as …

Precision medicine in kidney transplantation: just hype or a realistic hope?

E Nobakht, M Jagadeesan, R Paul… - Transplantation …, 2021 - journals.lww.com
genetic information are frequently used in kidney transplant recipients. Precision prescribing
of these medications could improve efficacy, … medicine in kidney transplantation and the …

Past, present, and future of regulatory T cell therapy in transplantation and autoimmunity

M Romano, G Fanelli, CJ Albany, G Giganti… - Frontiers in …, 2019 - frontiersin.org
… or efficacy of Treg infusion isolated from kidney transplant recipients on immunosuppression
with subclinical graft inflammation. However, following the results of this pilot study new

[HTML][HTML] Gene therapy clinical trials, where do we go? An overview

F Arabi, V Mansouri, N Ahmadbeigi - Biomedicine & Pharmacotherapy, 2022 - Elsevier
gene therapy, we reviewed current gene therapy products as well as gene therapies that may
be approved in the near futuregenetic diseases, may show higher efficacy and feasibility of …

Harnessing the B Cell Response in Kidney Transplantation–Current State and Future Directions

IJ Anwar, IF DeLaura, Q Gao, J Ladowski… - Frontiers in …, 2022 - frontiersin.org
therapies for their efficacy and safety in lowering antibody levels and permitting rejection-free
renal transplantation … are to assess efficacy in lowering antibody levels, leading to renal

Recent advances and clinical outcomes of kidney transplantation

C Thongprayoon, P Hansrivijit, N Leeaphorn… - Journal of Clinical …, 2020 - mdpi.com
… Although several studies have suggested the safe use of sodium glucose transport 2 (SGLT2)
inhibitors in kidney transplant recipients [128], future studies assessing their efficacy and …

Podocyte-targeted therapies—progress and future directions

K Meliambro, JC He, KN Campbell - Nature Reviews Nephrology, 2024 - nature.com
… for use in nephrology because of their efficacy in reducing proteinuria. These agents have
… and kidney biopsy samples from patients with recurrent FSGS after kidney transplantation

Investigational drugs for the treatment of kidney transplant rejection

LK van Vugt, MR Schagen, A de Weerd… - Expert Opinion on …, 2022 - Taylor & Francis
… of kidney transplant rejection. Potential therapeutic strategies and future directions are …
of its apparent efficacy, easier mode of administration and superior tolerability [Citation8]. In …

Recurrent Immunoglobulin A Nephropathy after Kidney Transplant—An Updated Review

HS Han, ML Lubetzky, NS Anandasivam, RA Cox… - Transplantology, 2023 - mdpi.com
… Turning our attention to mycophenolic acid (MPA) derivatives, most of the evidence of its
efficacy in IgAN is limited to native kidneys rather than recurrent disease. A meta-analysis …

[PDF][PDF] Current unmet needs in renal transplantation: a review of challenges and therapeutics

L Walsh, R Dinavahi - Front Biosci (Elite Ed), 2016 - article.imrpress.com
kidney transplantation but may occur in kidneys transplanted from a living donor as well.
IRI primary manifests in the immediate post-transplant … and efficacy of I5NP to prevent DGF. …