[PDF][PDF] General anesthetics

H Eilers, S Yost - Basic & clinical pharmacology, 2018 - academia.edu
… In recent years, this “unitary theory” of anesthetic action has … with the anesthesia rather than
through a direct teratogenic effect. … Ketamine relaxes bronchial smooth muscle and may be …

The effects of general anesthetics on synaptic transmission

X Hao, M Ou, D Zhang, W Zhao, Y Yang… - Current …, 2020 - ingentaconnect.com
… effects might result from direct action on the process … general anesthetics are important for
their synaptic actions. This section summarizes the presynaptic actions of general anesthetics

Inhalation anaesthetic isoflurane inhibits the muscarinic cation current and carbachol-induced gastrointestinal smooth muscle contractions

D Dryn, J Luo, M Melnyk, A Zholos, H Hu - European journal of …, 2018 - Elsevier
… The mechanisms of general anesthetics action on cells … components affected by general
anesthesia in relation to the … their coupling, while any direct muscarinic cation channel inhibition …

General Anesthetics

S Paulraj, M Lakshmanan - Introduction to Basics of Pharmacology and …, 2021 - Springer
vascular resistance (PVR): Volatile anesthetics produce minimal or no predictable effect on
pulmonary vascular smooth muscle. … for prompt onset of anesthetic action by the inhalational …

Unraveling interactions between anesthetics and the endothelium: update and novel insights

JA Aguirre, E Lucchinetti, AS Clanachan… - Anesthesia & …, 2016 - journals.lww.com
… also present in vascular smooth muscle and multiple blood … On diffusing to smooth muscle
cells, short-lived PGI 2 acts on … K + channels, or by direct effects on various other K + channels …

[HTML][HTML] Multimodal general anesthesia: theory and practice

EN Brown, KJ Pavone, M Naranjo - Anesthesia & analgesia, 2018 - journals.lww.com
… effectiveness of the local anesthetic in blocking action potential propagation depends critically
… and cortex due to direct inhibition of pyramidal neurons by the anesthetics in cortex and in …

[HTML][HTML] Ketamine, a clinically used anesthetic, inhibits vascular smooth muscle cell proliferation via PP2A-activated PI3K/Akt/ERK inhibition

Y Chang, JY Li, T Jayakumar, SH Hung… - International journal of …, 2017 - mdpi.com
… Intravenous anesthetics are firmly established to have direct effects on VSMCs, resulting in …
preliminary evidence on the antiproliferative mechanism of action of ketamine in VSMCs. This …

General Anesthetics

A Upaganlawar, A Sherikar… - Advances in …, 2020 - taylorfrancis.com
anesthetic agent acts mainly through inhibitory GABAA chloride channel. Clinically general
anesthetic causes stimulation of actions of … of uterine smooth muscle relaxation because of …

The effects of acetylcholinesterase inhibitors on morbidity after general anesthesia and surgery

D Shay, K Wongtangman, M Eikermann… - Neuropharmacology, 2020 - Elsevier
… administration during general anesthesia was … action of neostigmine and glycopyrrolate are
clinically relevant, we have highlighted relevant side-effects of glycopyrrolate such as arterial

[HTML][HTML] Regulatory effect of general anesthetics on activity of potassium channels

Y Li, J Xu, Y Xu, XY Zhao, Y Liu, J Wang, GM Wang… - Neuroscience …, 2018 - Springer
… Since the early 19th century, general anesthetics have … anesthesiology defines a complete
general anesthetic effect as including unconsciousness, amnesia, analgesia, and muscle