Polyfunctional Melan-A-specific tumor-reactive CD8+ T cells elicited by dacarbazine treatment before peptide-vaccination depends on AKT activation sustained by …
O Franzese, B Palermo, C Di Donna, I Sperduti… - …, 2016 - Taylor & Francis
Full article: Polyfunctional Melan-A-specific tumor-reactive CD8+ T cells elicited by dacarbazine
treatment before peptide-vaccination depends on AKT activation sustained by ICOS …
treatment before peptide-vaccination depends on AKT activation sustained by ICOS …
Generation of pure highly functional human anti-tumor specific cytotoxic T lymphocytes with stem cell-like memory features for melanoma immunotherapy
M Hamieh, JF Chatillon, E Dupel, F Bayeux… - Frontiers in …, 2021 - frontiersin.org
… Adoptive immunotherapy based on the transfer of anti-tumor cytotoxic T lymphocytes (CTLs) …
are injected without further purification, along with autologous activated T cells of unknown …
are injected without further purification, along with autologous activated T cells of unknown …
[HTML][HTML] Increased antitumor efficacy of PD-1-deficient melanoma-specific human lymphocytes
…, JM Heslan, J Shaffer, T Beauvais… - … for Immunotherapy of …, 2020 - ncbi.nlm.nih.gov
… properties of T cells for adoptive cell transfer purposes. So far, … gene editing in virus-specific
cytotoxic T lymphocytes (CTL)23 24 … Sorting and amplification of Melan-A specific T cells was …
cytotoxic T lymphocytes (CTL)23 24 … Sorting and amplification of Melan-A specific T cells was …
Low avidity T cells do not hinder high avidity T cell responses against melanoma
K Ioannidou, O Randin, A Semilietof… - Frontiers in …, 2019 - frontiersin.org
… of target cells to high avidity cytotoxic T cells. The … avidity, whereby Melan-A-specific T cells
are frequently detectable … TILs are regularly used for adoptive T cell therapy which can lead …
are frequently detectable … TILs are regularly used for adoptive T cell therapy which can lead …
CD8 T cell function and cross-reactivity explored by stepwise increased peptide-HLA versus TCR affinity
P Baumgaertner, J Schmidt, CM Costa-Nunes… - Frontiers in …, 2022 - frontiersin.org
… the tumor cell recognition capacity of distinct cytotoxic T cells. … recognition in adoptive T
cell immunotherapy, T cells were … /ELA vaccine-derived Melan-A-specific clones, pooled data …
cell immunotherapy, T cells were … /ELA vaccine-derived Melan-A-specific clones, pooled data …
Engineering a human plasmacytoid dendritic cell-based vaccine to prime and expand multispecific viral and tumor antigen-specific T-cells
…, K Laulagnier, JP Molens, H Benlalam, B Dreno… - Vaccines, 2021 - mdpi.com
… , which can be used in adoptive or active immunotherapy for the … Interestingly, an expansion
of Melan-A-specific T-cells was … , we cocultured them with CD8 + T-lymphocytes purified from …
of Melan-A-specific T-cells was … , we cocultured them with CD8 + T-lymphocytes purified from …
Identification of novel cancer-specific T cell targets by dissection of successful tumour-infiltrating lymphocyte therapy
C Rius Rafael - 2019 - orca.cardiff.ac.uk
Background – T cell-based cancer immunotherapy has emerged as the biggest … the key
effector cells are cytotoxic CD8+ T cells, which can detect anomalies in the proteome of cells that …
effector cells are cytotoxic CD8+ T cells, which can detect anomalies in the proteome of cells that …
Enhanced T-cell priming and improved anti-tumor immunity through lymphatic delivery of checkpoint blockade immunotherapy
C Mantilla-Rojas, FC Velasquez, JE Morton… - Cancers, 2022 - mdpi.com
… cytotoxic T-cells for anti-tumor immunity. Adoptive T-cell therapies use autologous T lymphocytes
… Nonetheless, we observed significant increases in Melan-A specific CD4 + and CD8 + …
… Nonetheless, we observed significant increases in Melan-A specific CD4 + and CD8 + …
Rapid and continued T-cell differentiation into long-term effector and memory stem cells in vaccinated melanoma patients
PO Gannon, P Baumgaertner, A Huber, EM Iancu… - Clinical Cancer …, 2017 - AACR
… Consequently, adoptive transfer of T SCM cells shows … Purified CD8 T cells were stained
with HLA-A*0201 analogue/… the differentiation of Melan-A–specific CD8 T cells based on the …
with HLA-A*0201 analogue/… the differentiation of Melan-A–specific CD8 T cells based on the …
High-throughput screening of human tumor antigen–specific CD4 T cells, including neoantigen-reactive T cells
C Costa-Nunes, A Cachot, S Bobisse, M Arnaud… - Clinical Cancer …, 2019 - AACR
… The CD4 T-cell library method (17) was adopted with the aim … Purified CD4 T cells were
sorted according to the naïve … the ex vivo detection of Melan-A–specific CD4 T cells in HLA-DQ6 …
sorted according to the naïve … the ex vivo detection of Melan-A–specific CD4 T cells in HLA-DQ6 …