A summary of the biological processes, disease-associated changes, and clinical applications of DNA methylation
GB Andersen, J Tost - DNA Methylation Protocols, 2018 - Springer
… that are part of the molecular machinery responsible for correct establishment and … DNA
methylation changes and genetic mutations co-occurring in the same tumors show different …
methylation changes and genetic mutations co-occurring in the same tumors show different …
The diverse roles of DNA methylation in mammalian development and disease
MVC Greenberg, D Bourc'his - Nature reviews Molecular cell biology, 2019 - nature.com
… and re-establishment of DNA methylation in embryonic, germline … into DNA methylation
gained from studying genetic diseases. … of recruiting the DNA methylation machinery to ensure …
gained from studying genetic diseases. … of recruiting the DNA methylation machinery to ensure …
[HTML][HTML] DNA methylation in human diseases
… of DNA methylation machinery is a phenomenal intersection that each of its ways can reveal
the mysteries of various diseases, … of genetic alterations is notably low in many diseases. All …
the mysteries of various diseases, … of genetic alterations is notably low in many diseases. All …
DNA hypermethylation in disease: mechanisms and clinical relevance
M Ehrlich - Epigenetics, 2019 - Taylor & Francis
… diseases, immunological diseases, atherosclerosis, and osteoporosis. In this review, I
discuss DNA hypermethylation in disease and … disruption of the epigenetic machinery [Citation56], …
discuss DNA hypermethylation in disease and … disruption of the epigenetic machinery [Citation56], …
DNA methylation in Parkinson's disease
U Wüllner, O Kaut, L deBoni, D Piston… - Journal of …, 2016 - Wiley Online Library
… the methylation machinery were identified in early, drug-naive sporadic PD patients (CBX5, …
, there is no doubt that in addition to genetic mutations, epigenetics and DNA methylation …
, there is no doubt that in addition to genetic mutations, epigenetics and DNA methylation …
[HTML][HTML] Understanding the relevance of DNA methylation changes in immune differentiation and disease
… Moreover, a subset of TFs that possess the ability to rearrange the epigenome (so-called
pioneer TFs) are able to interact with the epigenetic machinery, altering the DNA methylation …
pioneer TFs) are able to interact with the epigenetic machinery, altering the DNA methylation …
The interplay between DNA and histone methylation: molecular mechanisms and disease implications
… A central question in the field is how DNA methylation machineries interact with other …
DNA-modifying enzymes implicated in human diseases (Hansen et al, 1999). Genetic alterations in …
DNA-modifying enzymes implicated in human diseases (Hansen et al, 1999). Genetic alterations in …
Principles of DNA methylation and their implications for biology and medicine
… DNA methylation could provide a valuable tool for monitoring tissue dynamics and diagnosing
multiple diseases. … them and then recruited the methylation machinery. This secondary …
multiple diseases. … them and then recruited the methylation machinery. This secondary …
[HTML][HTML] Genetic impacts on DNA methylation: research findings and future perspectives
S Villicaña, JT Bell - Genome biology, 2021 - Springer
… disease onset and progression. In this review, we summarize recent milestones in characterizing
the human genetic basis of DNA methylation … , or even machine learning approaches …
the human genetic basis of DNA methylation … , or even machine learning approaches …
[HTML][HTML] The DNA methylation in neurological diseases
… of both genetic disorders and epigenetic alterations, … changes in DNA methylation machinery
can reduce the expression of Reelin and GAD67, encoding by RELN and GAD1 genes, …
can reduce the expression of Reelin and GAD67, encoding by RELN and GAD1 genes, …