… Although non-surgical treatment of CS is not available at this time, the increased awareness
… led to identification of potential targets for therapeutic interventions. FGFR tyrosine kinase …

… proved the potential application of MEK1 … of craniosynostosis processed above gave
potential strategy and new acknowledges to the pharmacological treatment of craniosynostosis, …

… pathogenesis of craniosynostosis, with … treatment options and highlight the potential of
mesenchymal stem cell-based suture regeneration as a therapeutic approach for craniosynostosis…

… genes within the cranial sutures and for the development of alternative nonsurgical treatment
strategies. … , Wang Y, Taub PJ, Jabs EW: Genetic basis of potential therapeutic strategies for …

… In addition to being part of a syndrome, craniosynostosis can be nonsyndromic, formed …
More than 50 nuclear genes that relate to craniosynostosis have been identified. Besides genetic …

… mandating an individualized, multispecialty approach to the successful treatment of each
patient. Currently, more than 180 syndromes are known to be associated with craniosynostosis. …

… Research about the genetic basis of craniosynostosis syndromes and their underlying
etiology has provided insights for their nonsurgical treatment. The identification of signaling …

… genes (single gene mutations, chromosome abnormalities, and polygenic background) may
all be predisposing factors for the disease. Genetic … the genes linked to craniosynostosis are …

… of unusual syndromic craniosynostosis not related to mutations in genes coding for FGFRs,
… of the genes undergoing intragenic mutations or CNVs; prevalence of craniosynostosis in …

… therapeutic strategies that may be used as a complement to the surgical treatment of …
that are associated with the development of craniosynostosis, we have done this narrative …