Mapping Mammary Tumor Traits in the Rat

MJ Flister, A Joshi, C Bergom, H Rui - Rat Genomics, 2019 - Springer
… results, we typically use virgin female rats that are 49–55 days of … developed a genetic mapping
strategy called the Consomic/… novel CXM strategy is specifically designed to map genetic

Mapping genetic modifiers of radiation-induced cardiotoxicity to rat chromosome 3

RA Schlaak, A Frei, AM Schottstaedt… - American Journal …, 2019 - journals.physiology.org
… This novel study reveals that heritable genetic factors have … SS-3 BN consomic rats, whereas
the SS rats had decreased FS … , we made use of a consomic panel derived from the SS and …

The rat: a model used in biomedical research

JR Smith, ER Bolton, MR Dwinell - Rat Genomics, 2019 - Springer
… This book provides detailed information on a number of … related to rats from southern East
Asia than they are to rats from … the then-current rat gene map, consisting of 214 genes and 11 …

Host genetic modifiers of nonproductive angiogenesis inhibit breast cancer

MJ Flister, SW Tsaih, A Stoddard, C Plasterer… - Breast cancer research …, 2017 - Springer
… (s) on rat chromosome 3 (RNO3) might decrease tumor vascular … BN3 consomic and SS rats
to examine proliferative capacity and … Here, we present a novel experimental model with key …

Integrating Biology With Rat Genomic Tools

MR Dwinell, AM Geurts - The Laboratory Rat, 2020 - Elsevier
… This improved genetic map was shown to impact the … Consomic and congenic strains
were developed to have a strain of rats or panel of rat strains to validate findings from genetic

Genetically Standardized Laboratory Rodents

F Benavides, J Jaubert - … Genes and Bugs: Monitoring Health and Genetics …, 2024 - Springer
… however, the first genetic studies in rats were conducted in the … rat strains that are used for
gene mapping, including complex … A complete panel of consomic strains consists of 21 strains, …

Taxonomy and stocks and strains

HJ Hedrich - The laboratory rat, 2020 - Elsevier
… of endonucleases, genetic modifications in rats have become … -density genetic maps with
the aim of mapping disease genes. … By comparing the characteristics of consomic strains with …

[图书][B] The laboratory rat

MA Suckow, FC Hankenson, RP Wilson, PL Foley - 2019 - books.google.com
… Historically, many genetically unique lines of rats have been … an American story, because
most of the strains of rats in use … Third, the story is literally one of ascendancy from the gutter …

Experimental models to define the genetic predisposition to liver cancer

RM Pascale, MM Simile, G Peitta, MA Seddaiu, F Feo… - Cancers, 2019 - mdpi.com
… Comparative functional genetic studies, in rats and mice … of consomic strains (CSs),
where an entire chromosome is … Detailed deletion mapping of chromosome 10 localized a …

… NIR fluorescence imaging and machine learning framework for stratifying high vs. low notch-Dll4 expressing host microenvironment in triple-negative breast cancer

S Shafiee, J Jagtap, M Zayats, J Epperlein, A Banerjee… - Cancers, 2023 - mdpi.com
Consomic Xenograft Model (CXM) as a strategy for mapping … green (ICG) through a tail
vein in tumor-bearing rats, and … vascular-specific Dll4 allele on rat chromosome 3 (RNO3) as a …