… reviews genetic modifier studies in DMD to date and discusses the effect of genetic modifiers
on … (inclusion of genotype-stratified subgroup analyses) and therapeutic approaches. The …

… muscular dystrophy (DMD) phenotype. This meta-analysis aims to estimate the association
of genetic … ) and secreted phosphoprotein 1 (SPP1) genes, among others, with age of loss of …

… genetic modifiers in DMD suggests that the ‘effect size’ of the … Effect size of genetic modifiers
can be quantitated in DMD by … Genetic modifiers to date all show about 1-2 years change in …

… Background and purpose: Duchenne muscular dystrophy (DMD) is a lethal progressive …
on the recent gene therapies for DMD that aim to compensate for dystrophin deficiency and the …

… (mdx) mice, have yielded valuable genetic modifiers of disease pathology.32 This Review
… consequences of genetic modifiers in the 2 most prevalent forms of muscular dystrophy in …

… variable phenotype known as Becker muscular dystrophy or X-linked … by other genetic modifiers
distinct from the DMD gene, … binding protein 4 (LBP4) gene and osteopontin, encoded by …

… In this paper, I present the significance of molecular diagnosis and the development of
mutation-based therapeutic strategies to complement or restore dystrophin expression. …

… genes different from DMD, that may influence the pathological consequences of dystrophin
… Here we aimed at describing the natural history of, and effect of GC treatment on respiratory …

… of GCs treatment, which is worth further discussing considering GCs has … genetic modifier
of the long-term effect of GCs treatment in Chinese patients with Duchenne muscular dystrophy…

… This study identified, among others, latent TGFβ binding protein 4 (LTBP4) as genetic modifier
of muscular dystrophy. Osteopontin, Jagged1, and LTBP4 act as extracellular mediators of …