Genistein: its role in breast cancer growth and metastasis

V Mukund - Current drug metabolism, 2020 - ingentaconnect.com
angiogenesis in mice have been inhibited by soy-rich diets of humans. [20, 21]. Genistein
conducted through in vivo experiments, the molecular processes of genistein should be well …

[HTML][HTML] Antiangiogenic phytochemicals constituent of diet as promising candidates for chemoprevention of cancer

AD Marrero, AR Quesada, B Martínez-Poveda… - Antioxidants, 2022 - mdpi.com
… Interestingly, recent evidence supports the ability of genistein, … addition, genistein is also a
potent inhibitor of angiogenesis, … a multitarget inhibitor of angiogenesis in vitro and in vivo [168,…

[HTML][HTML] Molecular changes underlying Genistein treatment of wound healing: a review

M Čoma, V Lachová, P Mitrengová, P Gál - Current Issues in Molecular …, 2021 - mdpi.com
… Furthermore, an in vivo study showed that genistein treatment can … Genistein was also able
to inhibit inducible nitric oxide synthase (… Furthermore, genistein modulated angiogenesis by …

[HTML][HTML] Genistein inhibits angiogenesis developed during rheumatoid arthritis through the IL-6/JAK2/STAT3/VEGF signalling pathway

WX Cheng, H Huang, JH Chen, TT Zhang… - Journal of orthopaedic …, 2020 - Elsevier
Genistein (GEN), a soy-derived isoflavone, has been validated that can effectively inhibit the
angiogenesis of several tumours. We thus carried out a study in vitro to investigate the effect …

[HTML][HTML] (R, S)-Equol 7-β-D-glucuronide, but not other circulating isoflavone metabolites, modulates migration and tubulogenesis in human aortic endothelial cells …

JA Giménez-Bastida, MÁ Ávila-Gálvez… - Food & Function, 2024 - pubs.rsc.org
… We aimed here to first assess the anti-angiogenic activities of … and their conjugated metabolites
of genistein and daidzein. … -II metabolite with the ability to inhibit tubulogenesis in vitro. …

Targeting tumor angiogenesis for cancer prevention

M García-Caballero, B Martínez Poveda… - Molecular Targets and …, 2016 - Springer
… tumor angiogenesis and the potential of the use of dietary derived inhibitors of angiogenesis
… In vitro, genistein has been shown to inhibit endothelial cell proliferation at concentrations …

Nutraceuticals and their role in tumor angiogenesis

A Rampino, T Annese, A Margari, R Tamma… - Experimental Cell …, 2021 - Elsevier
Genistein is a isoflavone that inhibits the proliferation and migration … vitro angiogenic and
metastatic potential of different tumor cell lines [65]. Moreover, genistein inhibits angiogenesis

Molecular and therapeutic targets of genistein in Alzheimer's disease

KP Devi, B Shanmuganathan, A Manayi… - Molecular …, 2017 - Springer
Genistein act as a promising dietary-derived anti-angiogenic compound for the prevention …
verified the in vitro and in vivo inhibitory effect of dietary soy isoflavone genistein on neuronal …

An overview on genistein and its various formulations

N Jaiswal, J Akhtar, SP Singh, F Ahsan - Drug research, 2019 - thieme-connect.com
… of genistein, only a small fraction of genistein aglycone was excreted through bile and a high
level of genistein … both in vitro and in vivo, in close comparison with pristine genistein and …

[PDF][PDF] Food & Function

JA Giménez-Bastida, MÁ Ávila-Gálvez… - novaresearch.unl.pt
… We aimed here to first assess the anti-angiogenic activities of … and their conjugated metabolites
of genistein and daidzein. … (ii) modulation of in vitro angiogenic mechanisms in this cell …