Profiling genome-wide DNA methylation

WS Yong, FM Hsu, PY Chen - Epigenetics & chromatin, 2016 - Springer
… In this review, we surveyed major methylation assays, … of DNA methylation profiling
techniques. The advances in microarray and sequencing technologies make genome-wide profiling

Genome-wide DNA methylation profiling using the methylation-dependent restriction enzyme LpnPI

R Boers, J Boers, B de Hoon, C Kockx, Z Ozgur… - Genome …, 2018 - genome.cshlp.org
… to perform DNA methylation analysis genome wide that provides … a DNA methylation-dependent
restriction enzyme, LpnPI, which specifically cuts 16 bp downstream from methylated and…

Genome-wide DNA methylation profiling reveals methylation markers associated with 3q gain for detection of cervical precancer and cancer

W Verlaat, PJF Snijders, PW Novianti, SM Wilting… - Clinical Cancer …, 2017 - AACR
… In conclusion, using an unbiased genome-wide DNA methylation profiling approach and …
and clinical cervical specimens, we identified 3 methylation markers, GHSR, SST, and ZIC1, …

Genome-wide DNA methylation profiling reveals novel epigenetic signatures in squamous cell lung cancer

YX Shi, Y Wang, X Li, W Zhang, HH Zhou, JY Yin… - BMC genomics, 2017 - Springer
… Their study provides an insightful perspective on smoking-associated DNA methylation and
genome-scale DNA methylation profile in LUSC and identified 5214 differentially methylated

Genome-wide DNA methylation profiling of peripheral blood reveals an epigenetic signature associated with severe COVID-19

MJ Corley, APS Pang, K Dody, PA Mudd… - Journal of leukocyte …, 2021 - academic.oup.com
… Here, we examined genome-wide DNA methylation (DNAm) profiles of peripheral blood
mononuclear cells from 9 terminally-ill, critical COVID-19 patients with confirmed SARS-CoV-2 …

Genome-wide DNA methylation profiling reveals cancer-associated changes within early colonic neoplasia

MP Hanley, MA Hahn, AX Li, X Wu, J Lin, J Wang… - Oncogene, 2017 - nature.com
… of the genome. Using this approach, we have shown that KRAS-mutant ACF harbor extensive
DNA methylation … In addition to promoter hypermethylation, we identify a large number of …

Genome-wide DNA methylation profiling in the superior temporal gyrus reveals epigenetic signatures associated with Alzheimer's disease

CT Watson, P Roussos, P Garg, DJ Ho, N Azam… - Genome medicine, 2016 - Springer
… We conducted genome-wide profiling of DNA methylation in STG bulk tissue samples
from 34 patients with AD and 34 non-demented controls. Quality control processing (see “Methods”…

Genome-wide DNA methylation profiling in infants born to gestational diabetes mellitus

X Weng, F Liu, H Zhang, M Kan, T Wang… - Diabetes Research and …, 2018 - Elsevier
… Global methylation landscapes We assessed the comprehensive DNA methylation profiles
with the 450k array in 30 women with GDM and 33 women with normal pregnancy. A total of …

Insights into the pathogenesis of anaplastic large-cell lymphoma through genome-wide DNA methylation profiling

MR Hassler, W Pulverer, R Lakshminarasimhan… - Cell reports, 2016 - cell.com
… Here, we describe the genome-wide DNA methylation signatures of NPM-ALK-positive …
large-cell lymphoma (ALCL). We find that ALK+ and ALK− ALCL share common DNA methylation

Genome wide DNA methylation profiling identifies specific epigenetic features in high-risk cutaneous squamous cell carcinoma

D Hervás-Marín, F Higgins, O Sanmartín… - PLoS …, 2019 - journals.plos.org
… In this work, we aimed to determine the overall genome DNA methylation profile in human
skin from pre- and post-malignant multistage cSCC using the Infinium DNA Methylation EPIC …