… effector domain that binds Ca 2+ -calmodulin, F-actin, and acidic phospholipids and thus
participates to the inhibition of fibrin formation [1] and platelet function [2]. The effector … effector …

… of the bacterial factors acting at the host-pathogen interface. Accurately identifying and …
effectors while offering new ways to probe the unique biology of these bacterial pathogens. …

… In a GTP-bound state, Rabs are active on the membrane and bind a variety of effector
proteins. The intrinsic GTPase activity of the Rab is modulated by the competing action of guanine…

… We identify the PDK orthologue Pkh1 as an effector of Stt4 and Mss4 PI kinase activities
at the PM (Figure 3). PI4P and PI(4,5)P 2 may recruit Pkh1 to the PM upon heat-induced …

… of effectors (eg, recruitment to a membrane), allosteric activation of effector enzymatic activity…
of fundamental and key aspects of their action and regulation. Defining the answers posed …

… technique in Drosophila, we identified a lethal mutation (40‐B89) … as the major downstream
effector of Mtm in growth control, we next … , we were surprised to see that increased F‐actin …

… There, they are proposed as downstream effectors of a … connection with tube growth, actin
organisation, and regulation of K + … of actin filaments could also play a role in establishing actin …

… binding, thereby modulating actin dynamics and vesicular trafficking (63). MARCKSL1 binds
to F-actin via its conserved effector domain but this does not lead to F-actin cross-linking in …

… a major downstream effector of the transcription factors SOX4 and SOX9, which regulate
liver and … A genetic screen identifies an LKB1-MARK signalling axis controlling the Hippo-YAP …

… structure and the actin regulatory activity of … genome. The structure of these chimeras is
illustrated in Fig. 3. All of the 5-ptase domains in these chimeras could complement the lethality of …