… Rab10 appears to regulate actin binding and endosomal tubulation, and could therefore …
and effectors regulate ER shape and dynamics. Interestingly, Rab5 has also been identified to …

… Cellular protein trafficking, the concerted action of moving … genome-wide phenotypic
profiles, was used to uncover new … recruitment of effector proteins, directing vesicle trafficking. …

… effector lobe (residues 1–86) and an allosteric lobe (residues 87–165). The effector lobe
interacts with RAS effectors … A genome-wide synthetic lethal RNAi screen in RAS-mutant tumors …

The organization of biological membranes into structurally and functionally distinct lateral
microdomains is generally accepted. From bacteria to mammals, laterally compartmentalized …

… of the SJ1 gene result in early postnatal lethality in both mice … , which displays properties
of a Rab5 effector (21, 22), was … and points to a shared site of action of the two proteins as a …

… -B and not with mutant VAPs, whereas actin, used as a loading control, was not found in the
… they regulate phototransduction. To identify molecular mechanisms that regulate the effector …

… act in regulating intercellular junctions in concert with actin … -10 and ARF-6 effectors to
indirectly assess activity changes of … Through synthetic lethality screening, it was discovered that …

… C and other key apoptotic effectors from the mitochondria into the … screening identified ACACA
(encoding ACC1) as a gene … and mechanism of action of this lethal compound remains to …

… regulation remain poorly defined. Here, we demonstrate that Sng1, a transmembrane protein,
is an effector of the Pkh/Ypk module and identify … Dnf-mediated flippase action or perturb …

… Viruses when enters into the host cell, they replicate and generate abundant copies of
their genome and continue to infect new hosts. The self-replication of single-stranded RNA …