Differential analysis of genome-wide methylation and gene expression in mesenchymal stem cells of patients with fractures and osteoarthritis
A Del Real, FM Pérez-Campo, AF Fernández… - Epigenetics, 2017 - Taylor & Francis
… of hMSCs in the pathogenesis of osteoporosis is still unclear. … to skeletal development are
differentially methylated in bone … differentially methylated regions in comparison with hMSCs …
differentially methylated in bone … differentially methylated regions in comparison with hMSCs …
Distinct DNA methylation profiles in bone and blood of osteoporotic and healthy postmenopausal women
S Reppe, TG Lien, YH Hsu, VT Gautvik, OK Olstad… - Epigenetics, 2017 - Taylor & Francis
… osteoporosis, we combined transcript profiling with DNA … findings among the 63 differentially
methylated CpGs (using FDR = … muscle reveals both direct and indirect regulation of muscle …
methylated CpGs (using FDR = … muscle reveals both direct and indirect regulation of muscle …
Alterations in DNA methylation profiles in cancellous bone of postmenopausal women with osteoporosis
Y Zhou, L Yang, H Wang, X Chen, W Jiang… - FEBS Open …, 2020 - Wiley Online Library
… methylation microarray analysis of the hip cancellous bone of patients with osteoarthritis
revealed differential methylation. … bone in bone development, we examined genome-wide DNA …
revealed differential methylation. … bone in bone development, we examined genome-wide DNA …
Comparative profiles of DNA methylation and differential gene expression in osteocytic areas from aged and young mice
Y Wei, J Fu, W Wu, J Wu - Cell Biochemistry and Function, 2020 - Wiley Online Library
… factors in age-related bone loss, either together or individually. … the differentially methylated
regions (DMRs), differentially … studies have revealed that SCFAs can improve the bone loss …
regions (DMRs), differentially … studies have revealed that SCFAs can improve the bone loss …
[HTML][HTML] Relationship between osteoporosis and osteoarthritis based on DNA methylation
Y Li, B Xie, Z Jiang, B Yuan - International journal of clinical and …, 2019 - ncbi.nlm.nih.gov
… [23] studied the genome-wide methylation profile of the bones in patients with hip … genome-wide
methylation analysis of bone samples revealed the regions with differential methylation …
methylation analysis of bone samples revealed the regions with differential methylation …
DNA methylation signatures of bone metabolism in osteoporosis and osteoarthritis aging-related diseases: an updated review
VV Visconti, I Cariati, S Fittipaldi, R Iundusi… - International Journal of …, 2021 - mdpi.com
… in bone biopsies from postmenopausal OP women, revealing … Profiling analysis identified
7316 differentially methylated … However, these differentially methylated regions of the genome …
7316 differentially methylated … However, these differentially methylated regions of the genome …
[HTML][HTML] Genome-wide DNA methylation analysis during osteogenic differentiation of human bone marrow mesenchymal stem cells
Y Cao, H Yang, L Jin, J Du, Z Fan - Stem cells international, 2018 - hindawi.com
… Our results also revealed that, along with the induced … the genes related to the differentially
methylated regions (DMGs) by … during local irradiation-induced bone loss in rats,” Scientific …
methylated regions (DMGs) by … during local irradiation-induced bone loss in rats,” Scientific …
Genome-wide identification of m6A-associated SNPs as potential functional variants for bone mineral density
XB Mo, YH Zhang, SF Lei - Osteoporosis International, 2018 - Springer
… Genome-wide mRNA expression was profiled using mRNA Human … This region shows
very high conservation, transcription level, and DNaseI hypersensitivity. The tracks sequentially …
very high conservation, transcription level, and DNaseI hypersensitivity. The tracks sequentially …
Identification of an epigenetic signature of osteoporosis in blood DNA of postmenopausal women
… methylation profile from controls increases with advanced stages of OP. We next overlapped
differentially methylated … Epigenome‐wide methylation analysis revealed 1233 significantly …
differentially methylated … Epigenome‐wide methylation analysis revealed 1233 significantly …
Genome‐wide DNA methylation profile analysis in thoracic ossification of the ligamentum flavum
T Fan, X Meng, C Sun, X Yang, G Chen… - Journal of Cellular …, 2020 - Wiley Online Library
… shortlisted the differentially methylated GO terms functionally related to bone development,
… shown to have distinct epigenomic profiles, and the Venn diagram revealed 65 significantly …
… shown to have distinct epigenomic profiles, and the Venn diagram revealed 65 significantly …