Decoding the regulatory landscape of ageing in musculoskeletal engineered tissues using genome-wide DNA methylation and RNASeq
MJ Peffers, K Goljanek-Whysall, J Collins, Y Fang… - PLoS …, 2016 - journals.plos.org
… engineered tissue types in ‘skeletal system morphogenesis’, ‘… such as osteoarthritis,
osteoporosis and tendinopathy. … were affected by the differentially methylated genes, we used …
osteoporosis and tendinopathy. … were affected by the differentially methylated genes, we used …
The roles of epigenetics regulation in bone metabolism and osteoporosis
F Xu, W Li, X Yang, L Na, L Chen, G Liu - Frontiers in cell and …, 2021 - frontiersin.org
… -wide signature of hMSCs from fracture patients shows differentially methylated regions
in … In 2017, Fernandez-Rebollo et al., analyzed genome wide DNA methylation profiles of …
in … In 2017, Fernandez-Rebollo et al., analyzed genome wide DNA methylation profiles of …
[HTML][HTML] Genome-wide DNA methylation profiling of articular cartilage reveals significant epigenetic alterations in Kashin-Beck disease and osteoarthritis
… differentially methylated CpG sites in KBD vs Normal, annotated to 264 hypermethylated and
368 hypomethylated genes. Comparing the DNA methylation profiles of … genetic bone and …
368 hypomethylated genes. Comparing the DNA methylation profiles of … genetic bone and …
New insights into the epigenetics of osteoporosis
JG Letarouilly, O Broux, A Clabaut - Genomics, 2019 - Elsevier
… transcript profiling with DNA methylation analyses in bone … for differential methylation of
RANKL at the bone tissue level … and colleagues revealed that the combination of methylation and …
RANKL at the bone tissue level … and colleagues revealed that the combination of methylation and …
DNA methylation analysis identifies key transcription factors involved in mesenchymal stem cell osteogenic differentiation
… our osteoblastogenesis differentially methylated regions with … , bone marrow adiposity has
been associated with bone loss in … in human pathological bone samples revealed a potential …
been associated with bone loss in … in human pathological bone samples revealed a potential …
Omics analysis of human bone to identify genes and molecular networks regulating skeletal remodeling in health and disease
S Reppe, HK Datta, KM Gautvik - Bone, 2017 - Elsevier
… Primarily omics studies on human bone in relation to osteoporosis … (CpGs) with differential
methylation between OP and OA, in … Bone shows a surprisingly high degree of anatomical site-…
methylation between OP and OA, in … Bone shows a surprisingly high degree of anatomical site-…
Integrative analysis of genomics and transcriptome data to identify potential functional genes of BMDs in females
YC Chen, YF Guo, H He, X Lin, XF Wang… - Journal of Bone and …, 2016 - academic.oup.com
… osteoporosis, we performed a system‐level study on bone … of microarray expression profiles
of transiliacal bone biopsies … which revealed a close relationship between muscle and bone…
of transiliacal bone biopsies … which revealed a close relationship between muscle and bone…
Recent advances in the epigenetics of bone metabolism
… Osteoporosis is a common form of metabolic bone disease … in BMD, and the differentially
methylated CpG sites most … Microarray-based profiling of circRNAs has also revealed that …
methylated CpG sites most … Microarray-based profiling of circRNAs has also revealed that …
[图书][B] The genetic and epigenetic determinants of osteoporosis
JA Morris - 2017 - search.proquest.com
… is a common, aging-related disease diagnosed primarily by measuring bone … Low bone
mineral density (BMD) is the most clinically relevant risk factor for osteoporosis and is used in …
mineral density (BMD) is the most clinically relevant risk factor for osteoporosis and is used in …
Identification of DNA methylation associated enrichment pathways in adults with non-specific chronic low back pain
… alterations and the role of bone maturation in cLBP. This study … change such as trauma,
osteoporosis, ankylosis spondylitis, and … Our goal was to identify differentially methylated patterns …
osteoporosis, ankylosis spondylitis, and … Our goal was to identify differentially methylated patterns …