Identification of differentially methylated regions in new genes associated with knee osteoarthritis
… have revealed significant differences in DNA methylation between OA and non-OA bone …
This work provides an assessment of differences in methylation profile between visually …
This work provides an assessment of differences in methylation profile between visually …
Use of integrative epigenetic and mRNA expression analyses to identify significantly changed genes and functional pathways in osteoarthritic cartilage
A He, Y Ning, Y Wen, Y Cai, K Xu, J Han… - Bone & joint …, 2018 - boneandjoint.org.uk
… differentially methylated genes, including 678 methylated and 587 demethylated genes.
Integrating the DNA methylation of mRNA expression profiles … findings, and reveal the potential …
Integrating the DNA methylation of mRNA expression profiles … findings, and reveal the potential …
Epigenetic regulation of bone remodeling and its impacts in osteoporosis
… , methylation, phosphorylation and ubiquitylation modifications, recent studies have revealed
other … Early studies revealed the association of hyperacetylated histones, which results in …
other … Early studies revealed the association of hyperacetylated histones, which results in …
Transcriptional profiling of human femoral mesenchymal stem cells in osteoporosis and its association with adipogenesis
YJ Choi, I Song, Y Jin, HS Jin, HM Ji, SY Jeong… - Gene, 2017 - Elsevier
… human MSCs from the bone marrow of typical severe osteoporosis patients and controls …
the NR4A family and bone metabolism. Our IPAs also revealed a possible relationship between …
the NR4A family and bone metabolism. Our IPAs also revealed a possible relationship between …
Effect of DNA methylation on gene transcription is associated with the distribution of methylation sites across the genome in osteoarthritis
P Yi, X Xu, J Yao, B Qiu - … and Therapeutic Medicine, 2021 - spandidos-publications.com
… The incidence of differential methylation varied in subregions of the genome and the … bone
marrow mesenchymal stem cells resulted in the impediment of postmenopausal osteoporosis (…
marrow mesenchymal stem cells resulted in the impediment of postmenopausal osteoporosis (…
Comprehensive analysis of epigenetics mechanisms in osteoporosis
Y Chen, Y Sun, X Xue, H Ma - Frontiers in Genetics, 2023 - frontiersin.org
… Osteoporosis is a metabolic disorder that bones become more … rate of bone formation is not
equal to the rate of bone loss, it … This research revealed a notable augmentation in the SOST …
equal to the rate of bone loss, it … This research revealed a notable augmentation in the SOST …
Novel regional age-associated DNA methylation changes within human common disease-associated loci
… genome-wide DNA methylomes aged 19–82 years, we identify 71 age-associated differentially
methylated regions … regards to age-related bone loss, shows methylation change in those …
methylated regions … regards to age-related bone loss, shows methylation change in those …
[HTML][HTML] Hypomethylation of the RUNX2 Gene Is a New Potential Biomarker of Primary Osteoporosis in Men and Women
B Yalaev, A Tyurin, K Akhiiarova… - International Journal of …, 2024 - mdpi.com
… Research shows that the expression of the RUNX2 gene is … postmenopausal osteoporosis
patients and affect bone tissue … differentially methylated region of RUNX2 and localized in this …
patients and affect bone tissue … differentially methylated region of RUNX2 and localized in this …
Identification of biomarkers associated with diagnosis of postmenopausal osteoporosis patients based on bioinformatics and machine learning
X Huang, J Ma, Y Wei, H Chen, W Chu - Frontiers in Genetics, 2023 - frontiersin.org
… bone loss and an increased risk of fracture, a systemic bone … analysis revealed ACACB and
WWP1 differential expression … RBCK1 were identified as differentially methylated genes. All …
WWP1 differential expression … RBCK1 were identified as differentially methylated genes. All …
Assessment of DNA methylation patterns in the bone and cartilage of a nonhuman primate model of osteoarthritis
G Housman, LM Havill, EE Quillen, AG Comuzzie… - Cartilage, 2019 - journals.sagepub.com
… one sample that is either from healthy bone, healthy cartilage, OA bone, or OA cartilage. In
… of Differential Methylation To identify sites that were significantly differentially methylated …
… of Differential Methylation To identify sites that were significantly differentially methylated …